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About This Item
Linear Formula:
CH3(CH2)11SH
CAS Number:
Molecular Weight:
202.40
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-984-1
Beilstein/REAXYS Number:
969337
MDL number:
assay
≥98%
InChI key
WNAHIZMDSQCWRP-UHFFFAOYSA-N
InChI
1S/C12H26S/c1-2-3-4-5-6-7-8-9-10-11-12-13/h13H,2-12H2,1H3
SMILES string
CCCCCCCCCCCCS
vapor density
7 (vs air)
Quality Level
bp
266-283 °C (lit.)
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General description
1-Dodecanethiol (DDT) is a premier alkanethiol for depositing highly ordered, hydrophobic Self-Assembled Monolayers (SAMs) on gold and noble metals. This ≥98% purity grade ensures crystalline-like molecular packing with minimal surface defects, critical for single-molecule electronics. As the gold standard for nanoparticle stabilization, its C12 chain offers the optimal balance between dense van der Waals packing and liquid-phase solubility, providing superior ease of handling compared to longer-chain analogs.
Application
As a versatile molecular bridge, DDT is essential for engineering intelligent interfaces and stimuli-responsive systems that enable precise interactions at the intersection of nanotechnology, biology, and electronics.
• Nanoparticle Capping: Provides a robust hydrophobic shell for Gold, CdS, and PbS nanocrystals, preventing aggregation and enabling solvent-phase processing.
• Steric Spacing: Acts as a critical "diluent" in mixed SAMs to precisely tune the lateral density of bulky bioreceptors (DNA/proteins), optimizing binding kinetics in biosensors.
• Molecular Electronics: Serves as a foundational dielectric spacer in molecular junctions to study electron tunneling across individual organic molecules.
• Quantum Dot Synthesis: Functions as a stable sulfur source for the solvothermal growth of magic-sized nanocrystals used in bio-imaging and optoelectronics.
• Interface Protection: Forms a non-conductive, anti-corrosive barrier on copper and germanium surfaces for futuristic microelectronics and medical implants.
• Nanoparticle Capping: Provides a robust hydrophobic shell for Gold, CdS, and PbS nanocrystals, preventing aggregation and enabling solvent-phase processing.
• Steric Spacing: Acts as a critical "diluent" in mixed SAMs to precisely tune the lateral density of bulky bioreceptors (DNA/proteins), optimizing binding kinetics in biosensors.
• Molecular Electronics: Serves as a foundational dielectric spacer in molecular junctions to study electron tunneling across individual organic molecules.
• Quantum Dot Synthesis: Functions as a stable sulfur source for the solvothermal growth of magic-sized nanocrystals used in bio-imaging and optoelectronics.
• Interface Protection: Forms a non-conductive, anti-corrosive barrier on copper and germanium surfaces for futuristic microelectronics and medical implants.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1C - Skin Sens. 1A
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
262.4 °F - closed cup
flash_point_c
128 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Synthesis, characterization and application of lead sulfide nanostructures as ammonia gas sensing agent.
Hassan K, et al.
International Journal of Electrochemical Science, 8(10), 11661-11679 (2013)
Pham Hong Phong et al.
Langmuir : the ACS journal of surfaces and colloids, 21(23), 10581-10586 (2005-11-03)
Ternary self-assembled monolayers (SAM) composed of 2-aminoethanethiol (AET), 2-mercaptoethanesulfonic acid (MES), and 1-dodecanethiol (DDeT) form two types of domains as if it were a two-component SAM: DDeT-rich hydrophobic domains and electrostatically stabilized hydrophilic domains composed of MES and AET on
Synthesis and characterization of PbS nanoparticles in an ionic liquid using single and dual source precursors.
Tshemese Z, et al.
Materials Science and Engineering, B, 227(7), 116-121 (2018)
Functions of 1-Dodecanethiol in the Synthesis and Post-treatment of Copper Sulfide Nanoparticles Relevant to Their Photocatalytic Applications.
Lihui C and Guohua L
ACS Applied Nano Materials, 1(9), 4587?4593-4587?4593 (2018)
Marta Gambucci et al.
Soft matter, 15(32), 6571-6580 (2019-08-01)
The comprehension and control of the interactions between nanoparticles and proteins at a molecular level are crucial to improve biomedical applications of nanomaterials and to develop nanosystems able to influence and regulate the conformational changes in proteins. In this work
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