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About This Item
Empirical Formula (Hill Notation):
Fe3O4
CAS Number:
Molecular Weight:
231.53
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
Quality Level
form
nanoparticles, solution
concentration
5 mg/mL in toluene
magnetization
>45 emu/g (at ambient temperature under 4500 Oe)
avg. part. size
10 nm
particle size
9-11 nm (TEM; conforms)
density
0.865 g/mL at 25 °C
SMILES string
O=[Fe].O=[Fe]O[Fe]=O
InChI
1S/3Fe.4O
InChI key
SZVJSHCCFOBDDC-UHFFFAOYSA-N
General description
Iron oxide(II,III), magnetic nanoparticles solution (Fe3O4) is an organic solvent dispersed nanoparticle solution, which can be synthesized by the thermal decomposition of iron acetylacetonate in 2-pyrrolidone. It is majorly used in biomedical applications due to its magnetic properties, particle size, and surface properties.
It contains <1.0% oleic acid stabilizing ligands.
It contains <1.0% oleic acid stabilizing ligands.
Concentration 5mg/ml includes total weight nanocrystals plus ligands.
Application
Fe3O4 can be used in the targeting and imaging of tumor cells for cancer therapy-based applications. It may also be used in the separation of tumor cells from fresh whole blood. It can also be used as an effective material in drug delivery systems and magnetic resonance imaging (MRI).
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signalword
Danger
Hazard Classifications
Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3
target_organs
Central nervous system
Storage Class
3 - Flammable liquids
wgk
WGK 3
flash_point_f
45.0 °F
flash_point_c
7.2 °C
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Nonpolymeric coatings of iron oxide colloids for biological use as magnetic resonance imaging contrast agents
Portet D, et al.
Journal of Colloid and Interface Science, 238(1), 37-42 (2001)
Antibody conjugated magnetic iron oxide nanoparticles for cancer cell separation in fresh whole blood
Xu H, et al.
Biomaterials, 32(36), 9758-9765 (2011)
Superparamagnetic nanoparticles for biomedical applications: possibilities and limitations of a new drug delivery system
Neuberger T, et al.
Journal of magnetism and magnetic materials, 293(1), 483-496 (2005)


