724459
Poly(N-isopropylacrylamide), carboxylic acid terminated
average Mn 10,000
Synonym(s):
NIPAM polymer, PNIPAM-COOH, Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM
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About This Item
Linear Formula:
(C6H11NO)nSCH2CH2CO2H
NACRES:
NA.23
UNSPSC Code:
12162002
Quality Level
form
powder
mol wt
average Mn 10,000 by GPC (THF w/ 5%TEA, PS, RI), average Mn 10,000
mp
>300 °C
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Related Categories
Application
Novel polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The carboxylic acid functional group can be used to conjugate a variety of biomolecules to the polymer chain.
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Avraham Halperin et al.
Langmuir : the ACS journal of surfaces and colloids, 28(48), 16623-16637 (2012-11-06)
Thermoresponsive tissue culture substrates based on PNIPAM brushes are used to harvest confluent cell sheets for tissue engineering. The prospect of clinical use imposes the utilization of culture medium free of bovine serum, thus suggesting conjugation with adhesion peptides containing
A C C Rotzetter et al.
Advanced materials (Deerfield Beach, Fla.), 24(39), 5352-5356 (2012-08-31)
Buildings can be effectively cooled by a bioinspired sweating-like action based on thermoresponsive hydrogels (PNIPAM), which press out their stored water when exceeding the lower critical solution temperature. The surface temperature is reduced by 15 °C compared to that of
G Chen et al.
Nature, 373(6509), 49-52 (1995-01-05)
There are many potential applications of 'intelligent' aqueous polymer systems in medicine, biotechnology, industry and in environmental problems. Many of these polymer systems undergo reversible phase transitions--for example, abrupt changes in volume--in response to external stimuli such as temperature, pH
Tatiya Trongsatitkul et al.
Colloids and surfaces. B, Biointerfaces, 103, 244-252 (2012-12-04)
The effect of PEGylation on the thermal response and protein adsorption resistance of crosslinked PNIPAm microgels was investigated. It was found that the presence of PEG, its molecular weight (M(n) 300 and 1100 g/mol) and its concentration (10, 20, and
Maria E Nash et al.
Stem cell reviews, 9(2), 148-157 (2013-01-29)
The facile regeneration of undifferentiated human mesenchymal stem cells (hMSCs) from thermoresponsive surfaces facilitates the collection of stem cells avoiding the use of animal derived cell detachment agents commonly used in cell culture. This communication proposes a procedure to fabricate
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