19-3310
2-Butanone
SAJ first grade, ≥99.0%
Synonym(s):
Ethyl methyl ketone, MEK, Methyl ethyl ketone
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About This Item
Linear Formula:
C2H5COCH3
CAS Number:
Molecular Weight:
72.11
PubChem Substance ID:
UNSPSC Code:
12352115
Beilstein/REAXYS Number:
741880
MDL number:
Assay:
≥99.0%
Grade:
SAJ first grade
Bp:
80 °C (lit.)
Vapor pressure:
71 mmHg ( 20 °C)
SMILES string
CC(CC)=O
InChI
1S/C4H8O/c1-3-4(2)5/h3H2,1-2H3
InChI key
ZWEHNKRNPOVVGH-UHFFFAOYSA-N
grade
SAJ first grade
vapor density
2.49 (vs air)
vapor pressure
71 mmHg ( 20 °C)
assay
≥99.0%
form
liquid
autoignition temp.
960 °F
expl. lim.
10.1 %
availability
available only in Japan
dilution
(for analytical testing)
refractive index
n20/D 1.379 (lit.)
bp
80 °C (lit.)
mp
−87 °C (lit.)
density
0.805 g/mL at 25 °C (lit.)
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Application
- Application of adsorptive stripping voltammetry based on PbFE for the determination of trace aluminum released into the environment during the corrosion process: The study highlights the role of ammonia buffer solutions in environmental monitoring techniques, particularly in tracing metal ion activities affecting corrosion processes (Wasąg J, Grabarczyk M, 2021).
- Long-Term Generation of Longitudinal Spin Order Controlled by Ammonia Ligation Enables Rapid SABRE Hyperpolarized 2D NMR: Demonstrates advanced NMR techniques facilitated by ammonia buffer solutions, enhancing molecular imaging capabilities essential in pharmaceutical research (Vaneeckhaute E, De Ridder S, Tyburn JM, Kempf JG, Taulelle F, Martens JA, Breynaert E, 2021).
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
target_organs
Central nervous system
supp_hazards
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
15.8 °F
flash_point_c
-9 °C
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S G Carmella et al.
Cancer research, 53(4), 721-724 (1993-02-15)
Metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a potent pulmonary carcinogen, have been quantified in the urine of 11 smokers. They were not detected in nonsmokers' urine. The metabolites, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronide, were detected in quantities of 0.23-1.0 and 0.57-6.5
L B Goldsmith et al.
Contact dermatitis, 19(5), 348-350 (1988-11-01)
Irritant contact dermatitis along with an increased transepidermal water loss can result from exposing the skin to solvents. A study of the interaction of various solvents with human stratum corneum was made using thin-layer chromatography. Comparison of 10 solvents (trichloroethylene
Sherille D Bradley et al.
Cancer immunology research, 3(6), 602-609 (2015-03-22)
Oncogene activation in tumor cells induces broad and complex cellular changes that contribute significantly to disease initiation and progression. In melanoma, oncogenic BRAF(V600E) has been shown to drive the transcription of a specific gene signature that can promote multiple mechanisms
Federico Mele et al.
Nature communications, 6, 6431-6431 (2015-03-17)
T helper (TH) cell polarization during priming is modulated by a number of signals, but whether polarization to a given phenotype also influences recall responses of memory TH cells is relatively unknown. Here we show that miR-181a is selectively induced
Jeong-Hwan Yoon et al.
Nature communications, 6, 7600-7600 (2015-07-22)
Transforming growth factor-β (TGF-β) and interleukin-6 (IL-6) are the pivotal cytokines to induce IL-17-producing CD4(+) T helper cells (TH17); yet their signalling network remains largely unknown. Here we show that the highly homologous TGF-β receptor-regulated Smads (R-Smads): Smad2 and Smad3
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