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Merck

124737

Glycolic acid

99%, solid, ReagentPlus®

Synonym(s):

Hydroxyacetic acid

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About This Item

Linear Formula:
HOCH2COOH
CAS Number:
79-14-1
Molecular Weight:
76.05
NACRES:
NA.21
PubChem Substance ID:
24847624
eCl@ss:
39021303
UNSPSC Code:
12352100
EC Number:
201-180-5
MDL number:
MFCD00004312
Beilstein/REAXYS Number:
1209322

Product Name

Glycolic acid, ReagentPlus®, 99%

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

InChI key

AEMRFAOFKBGASW-UHFFFAOYSA-N

SMILES string

OCC(O)=O

vapor pressure

0.00093 hPa ( 25 °C)

product line

ReagentPlus®

assay

99%

form

solid

Quality Level

200

pH

2 (20 °C, 50 g/L)

bp

(169 °C 336 °F at 998 hPa)

mp

75-80 °C (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

density

(1,26 g/cm3 at 20 °C - OECD Test Guideline 109)

functional group

carboxylic acid
hydroxyl

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Application

Glycolic acid (Hydroxyacetic acid) has been used in the preparation of PLGA-PEG-PLGA copolymer (PLGA = poly(lactic/glycolic, PEG = polyethylene glycol).

General description

Glycolic acid (Hydroxyacetic acid) is an α-hydroxy acid. Glycolic acid solutions having concentration of 70% and pH range of 0.08 to 2.75 are widely employed as superficial chemical peeling agents. Various oligomers or polymers of lactic and/or glycolic acid (low molecular weight) have been prepared. Glycolic acid can be determined via plant tissue coupled flow injection chemiluminescence biosensors, which can be used both as a plant-tissue based biosensor and chemiluminescence flow sensor.

Other Notes

Go to Redi-Dri™ Product Listing 798053

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

hcodes

H314,H332

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

>572.0 °F - (decomposition)

flash_point_c

> 300 °C - (decomposition)

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF7755V
WXBF7291V
WXBF3868V
WXBF2527V
WXBF2968V

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Sima Shahabi et al.
TheScientificWorldJournal, 2014, 420616-420616 (2015-01-13)
Gamma irradiation is able to affect various structural and biological properties of biomaterials In this study, a composite of Hap/PLGA-PEG and their ingredients were submitted to gamma irradiation doses of 25 and 50 KGy. Various properties such as molecular weight (GPC)
"A novel renewable plant tissue-based electrochemiluminescent biosensor for glycolic acid"
Zhu L, et al.
Sensors and Actuators B, Chemical, 98(2), 115-121 (2004)
?Plant Tissue-Based Chemiluminescence Flow Biosensor for Glycolic Acid?
Li B, et al.
Analytical Chemistry, 73(6), 1203-1206 (2001)
N Wang et al.
Journal of biomaterials science. Polymer edition, 8(12), 905-917 (1997-01-01)
A series of oligomers or low molecular weight polymers of lactic and/or glycolic acid has been synthesized with different molar ratios of lactic to glycolic acid. These oligomers have been characterized with respect to oligomer composition, molecular weight, intrinsic viscosity
F F Becker et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 22(5), 463-465 (1996-05-01)
Seventy percent glycolic acid solutions are being commonly used as superficial chemical peeling agents. The pH of these solutions ranges from 0.08 to 2.75. The histologic effects of these various pH solutions on human skin have not been studied. The
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