32553
Tinidazole
VETRANAL®, analytical standard
Synonym(s):
1-[2-(Ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole
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About This Item
Empirical Formula (Hill Notation):
C8H13N3O4S
CAS Number:
Molecular Weight:
247.27
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
243-014-4
Beilstein/REAXYS Number:
618182
MDL number:
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
CCS(=O)(=O)CCn1c(C)ncc1[N+]([O-])=O
InChI
1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3
InChI key
HJLSLZFTEKNLFI-UHFFFAOYSA-N
General description
Tinidazole belongs to the family of nitroimidazole compounds.
Application
Tinidazole may be used as an analytical reference standard for the determination of the analyte in:
- Tablet formulations and human serum samples by reversed phase-high performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2 - Muta. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Multi-residue method for the detection of veterinary drugs in distillers grains by liquid chromatography-Orbitrap high resolution mass spectrometry.
Kaklamanos G, et al.
Journal of Chromatography A, 1322, 38-48 (2013)
Separation and assay o f antiprotozoal imidazole derivatives (metronidazole, tinidazole and secnidazole) by RP-HPLC.
Alhalabi Z, et al.
International Journal of Pharmaceutical Sciences Review and Research, 13(1), 13-18 (2012)
Horatio B Fung et al.
Clinical therapeutics, 27(12), 1859-1884 (2006-03-02)
Tinidazole, a structural analogue of metrondazole, is an antiprotozoal agent that has been widely used in Europe and developing countries for >2 decades with established efficacy and acceptable tolerability. It was recently approved by the US Food and Drug Administration