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Merck

34218

Cefuroxime

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C16H16N4O8S
CAS Number:
55268-75-2
Molecular Weight:
424.39
NACRES:
NA.24
PubChem Substance ID:
329754904
UNSPSC Code:
41116107
EC Number:
259-560-1
MDL number:
MFCD00864889

Key Documents

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InChI key

JFPVXVDWJQMJEE-IZRZKJBUSA-N

InChI

1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1

SMILES string

[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@H]2NC(=O)\C(=N/OC)c3ccco3)C(O)=O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

Quality Level

100

Related Categories

General description

Chemical structure: β-lactam
Cefuroxime is a new broad-spectrum cephalosporin antibiotic, with increased stability to β-lactamases. It is actively used against gram-positive organisms, including penicillinase-producing staphylococci and non-β-lactamase-producing gram-negative bacteria.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Cefuroxime may be used as a reference standard in the determination of cefuroxime in plasma samples using high-performance liquid chromatography (HPLC).(3)

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL3041
BCBZ7539

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Ronit Confino-Cohen et al.
The journal of allergy and clinical immunology. In practice, 5(3), 669-675 (2017-05-10)
Penicillins are the drug family most commonly associated with hypersensitivity reactions. Current guidelines recommend negative skin tests (ST) before re-administering penicillins to patients with previous nonimmediate reactions (NIR). The objective of this study was to examine whether ST are necessary
Till Junker et al.
Swiss medical weekly, 142, w13616-w13616 (2012-09-06)
Surgical site infections (SSI) are the most common hospital-acquired infections among surgical patients, with significant impact on patient morbidity and health care costs. The Basel SSI Cohort Study was performed to evaluate risk factors and validate current preventive measures for
Sathish Srinivasan et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 35(8), 538-542 (2019-08-09)
To evaluate the posterior segment visualization in patients with small-aperture intraocular lens (IOL) implantation. In this prospective, comparative case series, 15 patients who had unilateral implantation of the small-aperture IOL in their non-dominant eyes were recruited. Their fellow eyes were
Grigorios Tsigkas et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 39(12), 840-847 (2016-06-24)
The purpose of this paper is to describe a novel minimally invasive endovascular model of progressive myocardial hypertrophy in rabbits as an experimental protocol of hypertrophic cardiomyopathy. Nine New Zealand White rabbits underwent transauricular aortic catheterization. Under fluoroscopy a bare
Elena Peira et al.
Pharmaceutics, 13(2) (2021-03-07)
Bevacizumab (BVZ), a recombinant humanized monoclonal antibody, has recently been proposed as a topical application in the treatment of anterior segment neovascularization; however, as there are some disadvantages in the administration of common eye-drops, ophthalmic topical drug delivery systems are
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