Key Documents

View All Documentation

69479

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

Name: <I>N</I>-Methyl-<I>N</I>-(trimethylsilyl)trifluoroacetamide
Brand: SIAL

derivatization grade (GC derivatization), LiChropur^™, ≥98.5%

Synonym(s):

N-Trimethylsilyl-N-methyl trifluoroacetamide, MSTFA

Select a Size

Change View

About This Item

Linear Formula:

CF₃CON(CH₃)Si(CH₃)₃

CAS Number:

24589-78-4

Molecular Weight:

199.25

UNSPSC Code:

23151817

NACRES:

NA.22

PubChem Substance ID:

329761689

EC Number:

246-331-6

Beilstein/REAXYS Number:

1941550

MDL number:

MFCD00000411

Assay:

≥98.5% (GC), ≥98.5%

Form:

liquid

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

grade

derivatization grade (GC derivatization)

Quality Level

200

vapor density

>1 (vs air)

vapor pressure

8.8 mmHg ( 27 °C)

assay

≥98.5% (GC), ≥98.5%

form

liquid

quality

LiChropur^™

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.38 (lit.), n20/D 1.380

bp

130-132 °C (lit.)

density

1.075 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C

InChI

1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3

InChI key

MSPCIZMDDUQPGJ-UHFFFAOYSA-N

Description

General description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a silylating reagent.

Application

Learn more in the Product Information

MSTFA may be used in silylation procedure to detemine steroid hormones 17α-ethinylestradiol (EE2) and estrone using GC-MS. MSTFA along with Trimethylsilyl chloride (TMCS) in eithyl acetate, acetonitrile and dichloromethane solvents leads to formation of trimethylsilyl (TMS) and tert-butyldimethylsilyl (TBS) derivatives.

Suitable for the derivatization of amines, amino acids, carboxyl, hydroxyamines, indolalkylamine, n-nitrosoamino acids, nucleosides, phenolalkylamines, serotonin and tryptamine.

Other Notes

Reagent for N-acetyl-N, trifluoroacetyl, trimethylsilyl, N-trimethylsilyl-N-trifluoroacetyl, and O-trimethylsilyl (TMS)

Powerful silylating agent

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Still not finding the right product?

Explore all of our products under N-Methyl-N-(trimethylsilyl)trifluoroacetamide

pictograms

GHS02,GHS07

signalword

Warning

hcodes

H226,H315,H319,H335

pcodes

P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

77.0 °F - closed cup

flash_point_c

25 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library