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Merck

81910

Propionic acid

≥99.5% (GC), liquid, puriss. p.a.

Synonym(s):

Acid C3, Propanoic acid, Propanyl acid

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About This Item

Linear Formula:
CH3CH2COOH
CAS Number:
Molecular Weight:
74.08
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39021305
UNSPSC Code:
12352100
EC Number:
201-176-3
MDL number:
Beilstein/REAXYS Number:
506071

Product Name

Propionic acid, puriss. p.a., ≥99.5% (GC)

Quality Level

InChI key

XBDQKXXYIPTUBI-UHFFFAOYSA-N

InChI

1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)

SMILES string

CCC(O)=O

vapor density

2.55 (vs air)

vapor pressure

2.4 mmHg ( 20 °C)

grade

puriss. p.a.

assay

≥99.5% (GC)

form

liquid

autoignition temp.

955 °F

expl. lim.

12.1 %

refractive index

n20/D 1.386 (lit.)
n20/D 1.386

bp

141 °C (lit.)

mp

−24-−23 °C (lit.)

solubility

organic solvents: soluble(lit.)
water: soluble(lit.)

density

0.993 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.5 mg/kg
Ba: ≤0.1 mg/kg
Bi: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.1 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.5 mg/kg
K: ≤0.5 mg/kg
Li: ≤0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Mo: ≤0.1 mg/kg
Na: ≤1 mg/kg
Ni: ≤0.1 mg/kg
Pb: ≤0.1 mg/kg
Sr: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

functional group

carboxylic acid

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Application

Propionic acid may be used in the synthesis of cellulose propionate (cellulose ester).

General description

Propionic acid is a linear monocarboxylic acid. It affords esters on reaction with alcohols or alkenes. It can be synthesized by reacting ethane, carbon monoxide and water. It participates as a precursor in the preparation of smallest azolium homoenolate intermediate.

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

129.2 °F - closed cup

flash_point_c

54 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Eagleson M.
Concise Encyclopedia Chemistry, 194-194 (1994)
Zhichao Jin et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(26), 9360-9363 (2015-05-28)
Direct β-carbon activation of propionic acid (C2H5CO2H) by carbene organocatalysis has been developed. This activation affords the smallest azolium homoenolate intermediate (without any substituent) as a 3-carbon nucleophile for enantioselective reactions. Propionic acid is an excellent raw material because it
Eagleson M.
Concise Encyclopedia Chemistry, 898-898 (1994)
L B Bindels et al.
British journal of cancer, 107(8), 1337-1344 (2012-09-15)
Metabolites released by the gut microbiota may influence host metabolism and immunity. We have tested the hypothesis that inulin-type fructans (ITF), by promoting microbial production of short-chain fatty acids (SCFA), influence cancer cell proliferation outside the gut. Mice transplanted with
Weiqiang Chen et al.
Journal of virology, 89(1), 581-593 (2014-10-24)
The recent global resurgence of arthritogenic alphaviruses, in particular chikungunya virus (CHIKV), highlights an urgent need for the development of therapeutic intervention strategies. While there has been significant progress in defining the pathophysiology of alphaviral disease, relatively little is known

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