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Merck

60356

Potassium phosphate dibasic

puriss. p.a., ACS reagent, anhydrous, ≥99.0% (T)

Synonym(s):

Dipotassium hydrogenphosphate, Dipotassium phosphate, sec.-Potassium phosphate

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About This Item

Linear Formula:
K2HPO4
CAS Number:
7758-11-4
Molecular Weight:
174.18
PubChem Substance ID:
329758898
eCl@ss:
38070212
UNSPSC Code:
12352302
NACRES:
NB.24
EC Number:
231-834-5
MDL number:
MFCD00011383
assay:
≥99.0% (T)
form:
powder or crystals
solubility:
water: soluble (completely)

Product Name

Potassium phosphate dibasic, puriss. p.a., ACS reagent, anhydrous, ≥99.0% (T)

InChI key

ZPWVASYFFYYZEW-UHFFFAOYSA-L

InChI

1S/2K.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2

SMILES string

[K+].[K+].OP([O-])([O-])=O

grade

ACS reagent
puriss. p.a.

assay

≥99.0% (T)

form

powder or crystals

impurities

≤0.001% total nitrogen (N)

loss

≤1.0% loss on drying, 105 °C

pH

8.5-9.6 (25 °C, 50 mg/mL in H2O)

solubility

water: soluble (completely)

anion traces

chloride (Cl-): ≤30 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
heavy metals: ≤5 ppm (by ICP-OES)

Quality Level

300

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Application


  • beta-lactoglobulin stabilized nanemulsions--Formulation and process factors affecting droplet size and nanoemulsion stability.: This study investigates the impact of formulation and process parameters on the stability and size of beta-lactoglobulin stabilized nanemulsions, potentially involving potassium phosphate dibasic in the formulation process (Ali et al., 2016).

  • Correlation of characteristics of gel extrusion module (GEM) tablet formulation and drug dissolution rate.: Examines how the characteristics of gel extrusion in tablet formulations influence drug dissolution rates, relevant for chemists looking into dissolution behavior and possibly involving potassium phosphate dibasic (Juang and Storey, 2003).

  • High-performance liquid chromatographic determination of phenylureas by photochemically-induced fluorescence detection.: Discusses a method for detecting phenylureas using high-performance liquid chromatography, which could involve potassium phosphate dibasic as a component of the mobile phase or sample preparation (Munoz de la Pena et al., 2002).

  • Assay and purity analysis of diatrizoate sodium in drug product by LC.: This research details a method for assaying and analyzing the purity of diatrizoate sodium, where potassium phosphate dibasic could be part of the chromatographic system (Chellquist et al., 1997).

General description

Potassium phosphate dibasic is a useful biological buffer having a pH in the range of 8.5-9.6. Potassium phosphate is present in various forms: monobasic (KH2PO4), dibasic (KH2PO4), and tribasic (K3PO4). Potassium phosphate buffers are widely employed in equilibrium dialysis, high performance liquid chromatography (HPLC) and affinity capillary electrophoresis studies.

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7880
BCCM9181
BCCL8768
BCCK5946
BCCH5097

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H Einarsson et al.
Applied and environmental microbiology, 61(2), 669-676 (1995-02-01)
In brined shrimp (ca. 3% NaCl), the effects of three different lactic acid bacteria bacteriocins (crude [6.54 x 10(sup10) U of bacteriocin activity {BU}/g] and purified [8.13 x 10(sup23) BU/g] nisin Z, carnocin UI49 [2.32 x 10(sup4) BU/g], and crude
Tessy Theres Baby et al.
Talanta, 80(5), 2016-2022 (2010-02-16)
A new type of amperometric glucose biosensor based on silicon dioxide coated magnetic nanoparticle decorated multiwalled carbon nanotubes (Fe(3)O(4)@SiO(2)/MWNTs) on a glassy carbon electrode (GCE) has been developed. MWNTs have been synthesized by catalytic chemical vapour decomposition (CCVD) of acetylene
John E Schiel et al.
Talanta, 65(2), 495-500 (2008-10-31)
Potassium phosphate buffer is often used in methods such as equilibrium dialysis, high performance liquid chromatography (HPLC), and affinity capillary electrophoresis (ACE) for characterizing the binding of drugs and hormones with proteins or other ligands within the body. In these
Dongwon Baek et al.
Plant physiology, 161(1), 362-373 (2012-11-17)
Although a role for microRNA399 (miR399) in plant responses to phosphate (Pi) starvation has been indicated, the regulatory mechanism underlying miR399 gene expression is not clear. Here, we report that AtMYB2 functions as a direct transcriptional activator for miR399 in
Teresa R O'Meara et al.
Nature communications, 6, 6741-6741 (2015-04-01)
Developmental transitions between single-cell yeast and multicellular filaments underpin virulence of diverse fungal pathogens. For the leading human fungal pathogen Candida albicans, filamentation is thought to be required for immune cell escape via induction of an inflammatory programmed cell death.
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