S8875
Sodium bicarbonate
ReagentPlus®, ≥99.5%, powder
Synonym(s):
Sodium hydrogen carbonate
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About This Item
Linear Formula:
NaHCO3
CAS Number:
Molecular Weight:
84.01
UNSPSC Code:
12352302
NACRES:
NA.21
PubChem Substance ID:
EC Number:
205-633-8
Beilstein/REAXYS Number:
4153970
MDL number:
assay:
≥99.5%
form:
powder
Product Name
Sodium bicarbonate, ReagentPlus®, ≥99.5%, powder
InChI key
UIIMBOGNXHQVGW-UHFFFAOYSA-M
InChI
1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
SMILES string
[Na+].OC([O-])=O
agency
suitable for EPA 300
product line
ReagentPlus®
assay
≥99.5%
form
powder
pKa (25 °C)
(1) 6.37, (2) 10.25 (carbonic acid)
density
2.16 g/mL at 25 °C (lit.)
Quality Level
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Application
Sodium bicarbonate can be used as a catalyst:
- To synthesize nitriles from the corresponding aldehydes and hydroxylamine hydrochloride in the presence of sodium sulfate as a co-catalyst.
- To prepare coumarin derivatives via intramolecular Wittig reaction of substituted 2-formylphenyl 2-bromoacetates.
- In the acetylation of primary alcohols and phenols by reacting with acetic anhydride.
General description
Sodium bicarbonate is commonly known as baking soda. It serves as a source of carbon dioxide and is used to prepare a variety of sodium salts. It is also an important pH-regulating agent.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Somjot S Brar et al.
Clinical journal of the American Society of Nephrology : CJASN, 4(10), 1584-1592 (2009-08-29)
Infusion of sodium bicarbonate has been suggested as a preventative strategy but reports are conflicting on its efficacy. The aim of this study was to assess the effectiveness of hydration with sodium bicarbonate for the prevention of contrast-induced acute kidney
Joshua C Tremblay et al.
The Journal of physiology, 593(3), 723-737 (2014-11-25)
Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown mechanisms. Oral administration of acetazolamide blunts the pulmonary vascular pressure response to acute hypoxia, thus permitting the observation of IPAVA blood flow with minimal
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This
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