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About This Item
Empirical Formula (Hill Notation):
C13H11Cl2NO2
Molecular Weight:
284.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
251-233-1
Beilstein/REAXYS Number:
1539058
MDL number:
grade
analytical standard
Quality Level
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
application(s)
agriculture
environmental
format
neat
SMILES string
CC12CC1(C)C(=O)N(C2=O)c3cc(Cl)cc(Cl)c3
InChI
1S/C13H11Cl2NO2/c1-12-6-13(12,2)11(18)16(10(12)17)9-4-7(14)3-8(15)5-9/h3-5H,6H2,1-2H3
InChI key
QXJKBPAVAHBARF-UHFFFAOYSA-N
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
11 - Combustible Solids
wgk
WGK 2
ppe
Eyeshields, Gloves, type N95 (US)
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Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat.
S Christiansen et al.
International journal of andrology, 31(2), 241-248 (2008-03-05)
The incidence of hypospadias is increasing in young boys, but it remains unclear whether human exposure to endocrine disrupting chemicals plays a role. Risk assessment is based on estimation of no-observed-adverse-effect levels for single compounds, although humans are exposed to
Kunifumi Inawaka et al.
Toxicology and applied pharmacology, 237(2), 178-187 (2009-03-24)
To verify whether anti-androgens cause transgenerational effects on spermatogenesis and DNA methylation in rats, gravid Crl:CD(SD) female rats (4 or 5/group, gestational day (GD) 0=day sperm detected) were intraperitoneally treated with anti-androgenic compounds, such as vinclozolin (100 mg/kg/day), procymidone (100
Anne Kirstine Müller et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 47(12), 2951-2962 (2009-08-12)
In this paper, we present a cumulative risk assessment of three anti-androgenic pesticides (vinclozolin, procymidone and prochloraz) using the relative potency factor (RPF) approach and an integrated probabilistic risk assessment (IPRA) model. RPFs for each substance were estimated for three