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Merck

43424

N-Isovalerylglycine

≥97.0% (GC)

Synonym(s):

N-(3-Methyl-1-oxobutyl)glycine, N-(3-Methylbutanoyl)glycine, [(3-Methylbutanoyl)amino]acetic acid

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About This Item

Empirical Formula (Hill Notation):
C7H13NO3
CAS Number:
Molecular Weight:
159.18
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
1766622
MDL number:
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Product Name

N-Isovalerylglycine, ≥97.0% (GC)

Quality Segment

assay

≥97.0% (GC)

form

powder or crystals

color

white to off-white

mp

87-90 °C

format

neat

InChI

1S/C7H13NO3/c1-5(2)3-6(9)8-4-7(10)11/h5H,3-4H2,1-2H3,(H,8,9)(H,10,11)

InChI key

ZRQXMKMBBMNNQC-UHFFFAOYSA-N

Biochem/physiol Actions

Isovalerylglycine is a byproduct of the catabolism of the amino acid leucine. Accumulation of isovalerylglycine occurs in Isovaleric Acidemia (IVA), an autosomal recessive disorder caused by mutations in the isovaleryl-CoA dehydrogenase gene. The deficiency of this enzyme in the metabolism of leucine leads to the accumulation of a series of isovaleryl-CoA metabolites, such as isovalerylglycine (IVG).


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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