D0815
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide
≥99% purity (HPLC), solid
Synonym(s):
DASPEI
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About This Item
Empirical Formula (Hill Notation):
C17H21IN2
CAS Number:
Molecular Weight:
380.27
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
223-248-3
MDL number:
Beilstein/REAXYS Number:
3783243
Product Name
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide, ≥99% (HPLC), solid
Quality Level
assay
≥99% (HPLC)
form
solid
color
red
mp
267 °C (dec.) (lit.)
solubility
DMSO: 0.5 mg/mL, methanol: soluble
εmax
36.0-41.0 at 457-463 nm in methanol
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
SMILES string
[I-].CC[n+]1ccccc1\C=C\c2ccc(cc2)N(C)C
InChI
1S/C17H21N2.HI/c1-4-19-14-6-5-7-17(19)13-10-15-8-11-16(12-9-15)18(2)3;/h5-14H,4H2,1-3H3;1H/q+1;/p-1
InChI key
AMAXNNVXIBDEMV-UHFFFAOYSA-M
Application
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) has been used for the labelling of hair cells in larval zebrafish.
Biochem/physiol Actions
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) accumulates in the mitochondria and has a large fluorescence Stokes shift. It is also used for the relative measurements of mitochondrial membrane potential.
Suitable as a mitochondrial stain in live cells.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Ru Zhang et al.
Biomolecules, 10(10) (2020-10-22)
Cochlear hair cells in human beings cannot regenerate after loss; however, those in fish and other lower species can. Recently, the role of inflammation in hair cell regeneration has been attracting the attention of scientists. In the present study, we
Development of a no-wash assay for mitochondrial membrane potential using the styryl dye DASPEI.
Jensen KH and Rekling JC
Journal of Biomolecular Screening, 15, 1071-1081 (2010)
Marina Yoffe et al.
Journal of experimental zoology. Part B, Molecular and developmental evolution, 334(7-8), 511-517 (2020-05-22)
The lateral line is the primary modality fish use to create a hydrodynamic image of their environment. These images contribute to a variety of behaviors, from rheotaxis to escape responses. Here we discern the contributions of visual and lateral line