Skip to Content
Merck

I1754

Isobutyric acid

99%

Synonym(s):

2-Methylpropionic acid

Sign In to View Organizational & Contract Pricing.

Select a Size

All Photos(4)

About This Item

Linear Formula:
(CH3)2CHCO2H
CAS Number:
79-31-2
Molecular Weight:
88.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24895944
EC Number:
201-195-7
Beilstein/REAXYS Number:
635770
MDL number:
MFCD00002658

Product Name

Isobutyric acid, 99%

InChI key

KQNPFQTWMSNSAP-UHFFFAOYSA-N

InChI

1S/C4H8O2/c1-3(2)4(5)6/h3H,1-2H3,(H,5,6)

SMILES string

CC(C)C(O)=O

vapor density

3.04 (vs air)

vapor pressure

1.5 mmHg ( 20 °C)

assay

99%

form

liquid

autoignition temp.

824 °F

expl. lim.

10 %

refractive index

n20/D 1.393 (lit.)

bp

153-154 °C (lit.)

mp

−47 °C (lit.)

density

0.95 g/mL at 25 °C (lit.)

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Isobutyric acid can be used:
  • to synthesize butyl isobutyrate via esterification with n-butanol using lipases
  • as a precursor for Methacrylic acid (MAA) through catalytic oxidative dehydrogenation. It can be produced through fermentative pathways

General description

Isobutyric acid is a carboxylic acid used as a building block in the production of active pharmaceutical ingredients (APIs).

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

131.0 °F - closed cup

flash_point_c

55 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCX9227
MKCT9170
MKCP9198
MKCK3340
MKCF5261

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

E M Faed et al.
Clinical and experimental pharmacology & physiology, 5(2), 195-198 (1978-03-01)
1. Two main conjugates of CPIB (2-[chlorophenoxy]-2-methylpropionic acid) are present in the urine of subjects taking clofibrate. The metabolites can be separated by thin-layer chromatography (TLC). 2. Both conjugates are hydrolysed by dilute alkali, but only one is hydrolysed by
A Vyalikh et al.
Physical chemistry chemical physics : PCCP, 9(18), 2249-2257 (2007-05-10)
Solid state deuterium NMR has been used to study the molecular motion of d(6)-isobutyric acid (d(6)-iBA) in the pure (unconfined) state and confined in the cylindrical pores of two periodic mesoporous silica materials (MCM-41, pore size 3.3 nm and SBA-15
Kimberlee S Mix et al.
Molecular pharmacology, 65(2), 309-318 (2004-01-27)
Matrix metalloproteinases (MMPs) degrade extracellular matrix components, and overexpression of these enzymes contributes to tissue destruction in arthritis. Of particular importance are the collagenases, MMP-1 and MMP-13, which have high activity against the interstitial collagens in cartilage. In this study
Julia Biermann et al.
Molecular vision, 17, 395-403 (2011-02-12)
Histone deacetylase inhibitors (HDACi) have neuroprotective effects under various neurodegenerative conditions, e.g., after optic nerve crush (ONC). HDACi-mediated protection of central neurons by increased histone acetylation has not previously been demonstrated in rat retinal ganglion cells (RGCs), although epigenetic changes
Livia H Morais et al.
Current biology : CB, 30(19), 3761-3774 (2020-08-22)
Birth by Caesarean (C)-section impacts early gut microbiota colonization and is associated with an increased risk of developing immune and metabolic disorders. Moreover, alterations of the microbiome have been shown to affect neurodevelopmental trajectories. However, the long-term effects of C-section
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service