O3379
1-Octacosanol
≥99% (GC)
Synonym(s):
n-Octacosanol, Octacosanol
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About This Item
Empirical Formula (Hill Notation):
C28H58O
CAS Number:
Molecular Weight:
410.76
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
209-181-2
MDL number:
Product Name
1-Octacosanol, ≥99% (GC)
InChI key
CNNRPFQICPFDPO-UHFFFAOYSA-N
InChI
1S/C28H58O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29/h29H,2-28H2,1H3
SMILES string
CCCCCCCCCCCCCCCCCCCCCCCCCCCCO
assay
≥99% (GC)
form
powder
lipid type
oils
storage temp.
2-8°C
Quality Level
Storage Class
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Amira N Kassis et al.
Atherosclerosis, 194(1), 153-158 (2006-11-25)
Policosanol is a mixture of higher aliphatic alcohols shown to have beneficial effects on plasma lipid levels in animals and humans. Over 50 studies have reported significant reductions in plasma cholesterol using policosanol obtained from Cuban sugar cane (Dalmer, La
Arrigo F G Cicero et al.
Complementary therapies in medicine, 13(4), 273-278 (2005-12-13)
We planned to carry out a pilot study to evaluate the efficacy and safety as an antihypercholesterolemic agent of a brand dietary supplement made of Monascus purpureus titrated extract, octacosanols and niacin on 111 Caucasian patients with low cardiovascular disease
Simonetta Oliaro-Bosso et al.
Lipids, 44(10), 907-916 (2009-09-19)
Octacosa-10,19-dien-1-ol is a newly synthesized long-chain alcohol, an unsaturated analogue of 1-octacosanol, the major component of policosanol, the purified natural mixture of different higher aliphatic alcohols obtained from sugarcane wax. Our efficient synthetic protocol (five steps with 50% overall yield)
Tao Wang et al.
Acta pharmacologica Sinica, 31(7), 765-774 (2010-06-29)
To investigate the protective effects of octacosanol in 6-hydroxydopamine-induced Parkinsonian rats and find whether octacosanol has effects on pro nerve growth factor (pro-NGF), NGF and the downstream effector proteins. Behavioral tests, enzymatic assay, tyrosine hydroxylase immunohistochemistry, TUNEL and Western blot
Christopher P F Marinangeli et al.
The British journal of nutrition, 97(2), 381-388 (2007-02-15)
Policosanols (PC) exist as very-long-chain alcohols derived from sugarcane currently used in many countries as a cholesterol-lowering therapy. PC purity and relative percentage composition have been suggested as primary reasons why the original Cuban PC (OPC) supplements possess lipid-lowering efficacy.
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