RAB0245

Mouse IL-10 ELISA Kit

Name: Mouse IL-10 ELISA Kit
Brand: SIGMA

for serum, plasma and cell culture supernatant

Synonym(s):

IL-10, Interleukin-10

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About This Item

NACRES:

NA.32

UNSPSC Code:

41116158

Product Name

Mouse IL-10 ELISA Kit, for serum, plasma and cell culture supernatant

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/mL
standard curve range: 78.13-5000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Il10(16153)

Related Categories

Enzyme-Linked Immunosorbent Assay (ELISA) Kits

Immunoassay Platform Solutions

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

IL-10 (interleukin 10) is an anti-inflammatory cytokine. In mouse, IL-10 produced by the CD4⁺Th2 (T helper cell 2) subset, inhibits the expression of cytokines specifically IFN-3 (interferon), by Thl (T helper cell 1) clones. mIL-10 has pleiotropic property and it interacts with various cell types such as thymocytes, cytotoxic T cells, mast cells, B cells, and macrophages. Polymorphisms in the IL-10 gene are associated with higher risk of preeclampsia, ankylosing spondylitis, nasopharyngeal carcinoma and basal cell carcinoma. B- cell specific IL-10 might have a suppressive role in systemic lupus erythematosus (SLE).

General description

The Mouse IL-10 (Interleukin-10) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of IL-10 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Mouse IL-10

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

GHS05

signalword

Warning

hcodes

H290

pcodes

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

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Clinical significance of IL-2 and IL-10 gene polymorphisms and serum levels in patients with basal-cell carcinoma.

Sobjanek M

Biomarkers in Medicine, 10(2), 185-195 (2016)

IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice.

Baglaenko Y

PLoS ONE, 11(3), e0150515-e0150515 (2016)

TNF-a and IL10 polymorphisms interaction increases the risk of ankylosing spondylitis in Chinese Han population.

Wang NG

International Journal of Clinical and Experimental Pathology, 8(11), 15204-15209 (2015)

The Influence of Bone Marrow-Secreted IL-10 in a Mouse Model of Cerulein-Induced Pancreatic Fibrosis.

Lin WR

BioMed Research International (2016)

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

de Waal Malefyt R

The Journal of Experimental Medicine, 174(5), 1209-1220 (1991)

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