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About This Item
Empirical Formula (Hill Notation):
C15H15NO4
CAS Number:
Molecular Weight:
273.28
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
216-483-8
MDL number:
Product Name
L-Thyronine,
InChI key
KKCIOUWDFWQUBT-AWEZNQCLSA-N
InChI
1S/C15H15NO4/c16-14(15(18)19)9-10-1-5-12(6-2-10)20-13-7-3-11(17)4-8-13/h1-8,14,17H,9,16H2,(H,18,19)/t14-/m0/s1
SMILES string
N[C@@H](Cc1ccc(Oc2ccc(O)cc2)cc1)C(O)=O
assay
≥98.0% (TLC)
form
powder
Quality Level
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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J S LoPresti et al.
The Journal of clinical endocrinology and metabolism, 70(5), 1479-1484 (1990-05-01)
A hidden pool of rT3 production represents a source of rT3 that is minimally reflected in circulating rT3 levels. To test for the existence of such a source of rT3 production in man, varying doses of the generalized deiodinase inhibitor
J Köhrle
Cellular and molecular life sciences : CMLS, 57(13-14), 1853-1863 (2001-02-24)
Thyroid hormones control growth, development, differentiation and metabolism in vertebrates. Most of the actions of the active thyroid hormone T3 (3,5,3'-triiodo-L-thyronine) are exerted via ligand-activated nuclear T3 receptors. Activation of the secretory product of the thyroid gland, L-thyroxine (3,3',5,5'-tetraiodo-L-thyronine), or
Martin A Paquette et al.
PloS one, 9(6), e101155-e101155 (2014-06-28)
Thyroid hormone (TH) exerts its effects by binding to the thyroid hormone receptor (TR), which binds to TH response elements (TREs) to regulate target gene expression. We investigated the relative ability of liganded homodimers TR and retinoid X receptor (RXR)
I J Chopra et al.
The Journal of clinical endocrinology and metabolism, 75(1), 189-194 (1992-07-01)
A highly sensitive, specific, and reproducible RIA has been developed to measure T3 sulfate (T3S). Only T4 sulfate cross-reacted significantly (approximately 3%) in the RIA; rT3 sulfate, T4, T3, rT3, and diiodothyronine cross-reacted less than 0.01%. T3S was bound by
D B Ramsden et al.
Biomedical mass spectrometry, 11(4), 193-198 (1984-04-01)
The mass spectral properties of four classes of derivatives of thyronine are discussed ( oxazolidinone , O-methyl oxazolidinone , O-acetyl oxazolidinone and N,O- diheptafluorobutyryl methyl ester). An assay for thyronine in human urine is described based on the N,O- diheptafluorobutyryl
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