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20324AST

Astec® CYCLOBOND I 2000 RSP Chiral (5 μm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

Synonym(s):

Chiral HPLC column 2000 RSP

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
25 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
cyclodextrin, beta- phase
Pore size:
100 Å pore size
Matrix:
silica particle platform, fully porous particle

Key Documents

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Product Name

Astec® CYCLOBOND I 2000 RSP Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

material

stainless steel column

Quality Level

100

agency

suitable for USP L45

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-50 °C temperature, 172 bar pressure (2500 psi)

technique(s)

HPLC: suitable, LC/MS: suitable

L × I.D.

25 cm × 4.6 mm

matrix

silica particle platform, fully porous particle

matrix active group

cyclodextrin, beta- phase

particle size

5 μm

pore size

100 Å pore size

operating pH

3.5-7

separation technique

chiral

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General description

The hydroxyl groups on the surface of the β-cyclodextrin are reacted with (R,S)-propylene oxide to yield a general purpose chiral stationary phase. It has the added property of separating non-aromatic structures such as t-boc amino acids, for which it is a standard methodology.

  • Bonded phase: (R,S)-Hydroxypropyl modified β-cyclodextrin

Application

Astec® CYCLOBOND I 2000 RSP chiral HPLC column is basically comprised of native and derivatized β and γ cyclodextrins. It has been used for numerous chiral separations via selectively trapping the organic molecules in the cyclodextrin cavity.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
301008-06
301008-05
301008-04
301008-03
301008-02

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Rare case of rhabdomyolysis with therapeutic doses of phendimetrazine tartrate.
DK, et al.
American Journal of Therapeutics, 13(2), 175-176 (2006)
C Pham-Huy et al.
Journal of chromatography. B, Biomedical sciences and applications, 700(1-2), 155-163 (1997-12-09)
The simultaneous determination of methadone (Mtd) enantiomers and its major metabolite, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), in human urine and serum by enantioselective HPLC using a new Cyclobond 1-2000 RSP column is described. After alkaline extraction from urine or serum with estazolam as
Solid-phase extraction of methadone enantiomers and benzodiazepines in biological fluids by two polymeric cartridges for liquid chromatographic analysis
He, Hua, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 814 (2), 385-391 (2005)
Liquid chromatographic separation of zalcitabine and its stereoisomers
Scypinski, Stephen; Ross, Arthur J.
Journal of Chromatography. B, Biomedical Sciences and Applications, 12 (10), 1271-1276 (1994)
High-performance liquid chromatographic determination of the isomeric purity of a series of dioxolane nucleoside analogues
Di Marco, M.P., et al.
Journal of Chromatography A, 645 (1), 107-114 (1993)
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