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Merck

1381709

USP

Menthol

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(−)-Menthol, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol, 5-Methyl-2-(1-methylethyl)cyclohexanol

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About This Item

Empirical Formula (Hill Notation):
C10H20O
CAS Number:
Molecular Weight:
156.27
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1902293
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Product Name

Menthol, United States Pharmacopeia (USP) Reference Standard

InChI key

NOOLISFMXDJSKH-KXUCPTDWSA-N

SMILES string

CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O

InChI

1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1

grade

pharmaceutical primary standard

API family

menthol

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Menthol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Menthol Lozenges
  • Tetracaine and Menthol Ointment
  • Benzocaine and Menthol Topical Aerosol®
  • Anethole

General description

Menthol is an alcohol extracted from various mint oils or prepared synthetically. It exists in two forms: levorotatory (l-menthol), which can be found in natural or synthetic sources, and racemic (dl-menthol).

Other Notes

Sales restrictions may apply.

Legal Information

Aerosol is a registered trademark of Cytec Technology Corp.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

201.2 °F - closed cup

flash_point_c

94 °C - closed cup


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Tetracaine and Menthol Ointment?
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4294-4294 (2013)
Menthol
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 49(5) (2022)
Benzocaine and Menthol Topical Aerosol
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(1), 518-518 (2016)
Menthol Lozenges
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(2), 2782-2782 (2013)
Titeyut Wongsanao et al.
Pharmaceutical biology, 59(1), 854-859 (2021-07-02)
Psidium guajava L. (Myrtaceae) leaf contains a wide variety of bioactive compounds that contribute valuable effects on human well-being. This study investigates the influence of guava leaf extract-menthol toner on thermoregulation, including perspiration, skin temperature, and recovery heart rate. This

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