202398
Poly(ethylene glycol)
average Mn 400, hydroxyl
Synonym(s):
Polyethylene glycol, PEG
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:
Product Name
Poly(ethylene glycol), average Mn 400
form
viscous liquid
Quality Level
mol wt
Mn 380-420, average Mn 400
greener alternative product characteristics
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
refractive index
n20/D 1.466
pH
4.5-7.5
viscosity
7.3 cSt(210 °F)(lit.)
mp
4-8 °C (lit.)
density
1.128 g/mL
Ω-end
hydroxyl
α-end
hydroxyl
greener alternative category
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
General description
Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are non-toxic, FDA-approved, generally non-immunogenic, and frequently used in many biomedical applications including bioconjugation, drug delivery, surface functionalization, and tissue engineering. In drug delivery, PEGs can be used as linkers for antibody-drug conjugates (ADCs) or as a surface coating on nanoparticles to improve systemic drug delivery.
Application
Poly(ethylene glycol) (PEG) has been used as a coating agent for the synthesis and in vitro safety assessment of magnetic bacterial cellulose (MBC) pellicles, performed on porcine aortic smooth muscle cells (PAOSMC). PEG provides a compatible surface for cell culture, since uncoated iron oxide NPs are considered cytotoxic to cells. It has also been used as a plasticizer in investigating the effectiveness of polyvinylpyrrolidone microneedles for transdermal delivery of functional collagen using porcine skin, adult human skin analog and human foreskin. Microneedles obtained, were reportedly characterized by various analytical and bio-analytical techniques.
Used in conjunction with carbon black to form a conductive composite. Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.
Solvent for greener fluorination of acetoacetamides with Selectfluor®.
Catalyst-free and highly selective electrophilic mono-fluorination of acetoacetamides: facile and efficient preparation of 2-fluoroacetoacetamides in PEG-400
Catalyst-free and highly selective electrophilic mono-fluorination of acetoacetamides: facile and efficient preparation of 2-fluoroacetoacetamides in PEG-400
Legal Information
Selectfluor is a registered trademark of Merck KGaA, Darmstadt, Germany
Still not finding the right product?
Explore all of our products under Poly(ethylene glycol)
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Changxin Wan et al.
Cancer research, 81(1), 158-173 (2020-11-08)
Immune therapies have had limited efficacy in high-grade serous ovarian cancer (HGSC), as the cellular targets and mechanism(s) of action of these agents in HGSC are unknown. Here we performed immune functional and single-cell RNA sequencing transcriptional profiling on novel
Synthesis and in vitro safety assessment of magnetic bacterial cellulose with porcine aortic smooth muscle cells
Pastrana FH, et al.
Journal of Biomedical Materials Research Part A, 104(11), 2801-2809 (2016)
Transdermal delivery of functional collagen via polyvinylpyrrolidone microneedles
Sun W, et al.
Annals of Biomedical Engineering, 43(12), 2978-2990 (2015)