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61250

DL-Kynurenine

Name: <SC>DL</SC>-Kynurenine
Brand: ALDRICH

≥95.0% (NT), for peptide synthesis

Synonym(s):

2-Amino-3-(2-aminobenzoyl)propionic acid, 2-Amino-4-(2-aminophenyl)-4-oxobutyric acid

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₂N₂O₃

CAS Number:

343-65-7

Molecular Weight:

208.21

NACRES:

NA.22

PubChem Substance ID:

57651839

UNSPSC Code:

12352209

EC Number:

206-445-9

MDL number:

MFCD00025194

Beilstein/REAXYS Number:

2697333

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Properties

Product Name

DL-Kynurenine, ≥95.0% (NT)

Quality Level

100

assay

≥95.0% (NT)

form

powder

mp

~235 °C (dec.)

application(s)

peptide synthesis

SMILES string

NC(CC(=O)c1ccccc1N)C(O)=O

InChI

1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)

InChI key

YGPSJZOEDVAXAB-UHFFFAOYSA-N

Description

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation.

Adam Kosti et al.

Genome biology, 21(1), 195-195 (2020-08-09)

RNA-binding proteins (RBPs) function as master regulators of gene expression. Alterations in RBP expression and function are often observed in cancer and influence critical pathways implicated in tumor initiation and growth. Identification and characterization of oncogenic RBPs and their regulatory

Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial.

Asma Kazemi et al.

Clinical nutrition (Edinburgh, Scotland), 38(2), 522-528 (2018-05-08)

Disturbance in the equilibrium of the gut microbiota has been involved in the pathophysiology of depression. Probiotics have the potential to healthfully modulate the gut microbiome. Prebiotics could also be effective by stimulation of growth of some bacterial species in

Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria.

Dag Holmberg et al.

Malaria journal, 16(1), 303-303 (2017-07-30)

One-fourth of children with cerebral malaria (CM) retain cognitive sequelae up to 2 years after acute disease. The kynurenine pathway of the brain, forming neuroactive metabolites, e.g. the NMDA-receptor antagonist kynurenic acid (KYNA), has been implicated in long-term cognitive dysfunction in

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