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Merck

75490

DL-Ornithine monohydrochloride

≥99.0% (AT)

Synonym(s):

(±)-2,5-Diaminopentanoic acid monohydrochloride

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About This Item

Linear Formula:
NH2(CH2)3CH(CO2H)(NH2) · HCl
CAS Number:
Molecular Weight:
168.62
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
213-956-0
Beilstein/REAXYS Number:
4153338
MDL number:
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InChI key

GGTYBZJRPHEQDG-UHFFFAOYSA-N

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H

SMILES string

Cl.NCCCC(N)C(O)=O

assay

≥99.0% (AT)

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

~233 °C (dec.)

application(s)

peptide synthesis

Quality Level

Application

DL-Ornithine monohydrochloride may be used as a starting material in the synthesis of (-)-(1-2H)putrescine dihydrochloride via enzymatic decarboxylation.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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The Stereochemistry of the Enzymic Decarboxylation of l-Arginine and of l-Ornithine
Richards JC and Spenser ID
Canadian Journal of Chemistry, 60(22), 2810-2820 (1982)
Juan C Marini et al.
American journal of physiology. Endocrinology and metabolism, 303(11), E1348-E1353 (2012-10-18)
Citrulline is an amino acid synthesized in the gut and utilized for the synthesis of the conditionally essential amino acid arginine. Recently, the origin of the ornithine utilized for citrulline synthesis has become a matter of discussion. Multiple physiological factors
Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming
D Amelio et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 164(2), 356-362 (2012-11-06)
The Frank-Starling law is a fundamental property of the vertebrate myocardium which allows, when the end-diastolic volume increases, that the consequent stretch of the myocardial fibers generates a more forceful contraction. It has been shown that in the eel (Anguilla
Osama I Abd El-Salam et al.
Molecules (Basel, Switzerland), 17(12), 14510-14521 (2012-12-12)
A series of macrocyclic imides and Schiff-bases have been prepared via the cyclocondensation of pyridine-2,6-dicarbonyl dichloride (1) with L-ornithine methyl ester to give the corresponding macrocyclic bisester 2. Treatment of 2 with hydrazine hydrate gave macrocyclic bisacid hydrazide 3, which

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