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5.05016

CX546

Name: CX546
Brand: MM

Synonym(s):

CX546, AMPA Positive Allosteric Modulator, CX546, CX-546, CX 546

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₇NO₃

CAS Number:

215923-54-9

Molecular Weight:

247.29

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD01860868

Assay:

≥98% (TLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

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Properties

assay

≥98% (TLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

off-white

solubility

DMSO: soluble

storage temp.

2-8°C

SMILES string

N3(CCCCC3)C(=O)c1cc2c(cc1)OCCO2

InChI

1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2

InChI key

LJUNPHMOGNFFOS-UHFFFAOYSA-N

Description

General description

A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation.

Biochem/physiol Actions

Primary Target
AMPA

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Silverman, L., et al. 2013. Neuropharmacol.64, 268.
Peleg-Raibstein, D., et al. 2012. Curr. Antipsych.2012, 361.

Schitine, C., et al. 2012. Eur. J. Neurosci.35, 1672.
Lipina, T., et al. 2006. Neuropsychopharmacology.32, 745.
Arai, C., et al. 2004. Neurosci.123, 1011.
Nagarajan, N., et al. 2001. Neuropharmacol.41, 650.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c