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Merck

44208

L-Lysine hydrochloride solution

100 mM amino acid in 0.1 M HCl, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C6H14N2O2 · HCl
CAS Number:
Molecular Weight:
182.65
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5460909
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InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

SMILES string

Cl.NCCCC[C@H](N)C(O)=O

InChI key

BVHLGVCQOALMSV-JEDNCBNOSA-N

grade

analytical standard

form

liquid

analyte chemical class(es)

amino acids, peptides, proteins

concentration

100 mM amino acid in 0.1 M HCl

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

colorless

application(s)

food and beverages

format

single component solution

storage temp.

2-8°C

Quality Level

General description

L-Lysine hydrochloride is one of the essential amino acids which usually finds applications in the treatment of shingles and genital as well mouth lesions attributed to herpes zoster and herpes simplex virus, respectively.

Application

L-Lysine hydrochloride may be used as a reference standard for the determination of L-lysine hydrochloride in pharmaceutical dosage form by high resolution high performance liquid chromatography (HR-HPLC). It may be used as a precursor of lysine for its determination in breath condensate by isotope dilution hydrophilic-interaction liquid chromatography combined with tandem mass spectrometry (HILIC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

ppe

Eyeshields, Gloves

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids


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Simultaneous determination of the advanced glycation end product Nε-carboxymethyllysine and its precursor, lysine, in exhaled breath condensate using isotope-dilution-hydrophilic-interaction liquid chromatography coupled to tandem mass spectrometry
Schettgen T, et al.
Analytical and Bioanalytical Chemistry, 387(8), 2783-2791 (2007)
Development and validation of new hplc method for simultaneous estimation of L-lysine hydrochloride and L-carnitine-L-tartrate in pharmaceutical dosage form.
Qadir MA, et al.
Indian Journal of Pharmaceutical Sciences, 77(4), 434-434 (2015)
Guntur Fibriansah et al.
Nature communications, 6, 6341-6341 (2015-02-24)
Dengue virus (DENV) infects ~400 million people annually. There is no licensed vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a naturally occurring dengue infection consists of highly neutralizing antibodies. Here we show that
L Dierickx et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(2), 502-509 (2014-07-11)
The aim of this study was to develop by means of co-extrusion a multilayer fixed-dose combination solid dosage form for oral application characterized by immediate release for both layers, the layers containing different drugs with different water-solubility. In this study
Jing Li et al.
American journal of physiology. Cell physiology, 306(10), C943-C960 (2014-03-22)
The human solute carrier (SLC26) family of anion transporters consists of 10 members (SLCA1-11, SLCA10 being a pseudogene) that encode membrane proteins containing ~12 transmembrane (TM) segments with putative N-glycosylation sites (-NXS/T-) in extracellular loops and a COOH-terminal cytosolic STAS

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