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Merck

T6501

Triamcinolone acetonide

analytical standard

Synonym(s):

9α-Fluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide, 9α-Fluoro-16α-hydroxyprednisolone 16α,17α-acetonide

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About This Item

Empirical Formula (Hill Notation):
C24H31FO6
CAS Number:
76-25-5
Molecular Weight:
434.50
NACRES:
NA.24
PubChem Substance ID:
329826845
UNSPSC Code:
41116107
EC Number:
200-948-7
MDL number:
MFCD00056834

Key Documents

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Product Name

Triamcinolone acetonide, analytical standard

InChI key

YNDXUCZADRHECN-JNQJZLCISA-N

InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

grade

analytical standard

assay

≥99%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

100

Gene Information

human ... NR3C1(2908)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

hcodes

H302,H360

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV6841
MKCQ6357
MKCN7288
MKCH0033
MKCD5994

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Hiroshi Kunikata et al.
American journal of ophthalmology, 155(6), 1028-1037 (2013-03-16)
To investigate the role of intravitreal injection of triamcinolone acetonide (IVTA) in preventing photoreceptor apoptosis in eyes with rhegmatogenous retinal detachment (RRD) by measuring cytokine levels in the aqueous humor before and after IVTA. Prospective, nonrandomized, interventional case series. setting:
Jill S Waibel et al.
Lasers in surgery and medicine, 45(3), 135-140 (2013-03-06)
Hypertrophic scars and contractures are common following various types of trauma and procedures despite skilled surgical and wound care. Following ample time for healing and scar maturation, many millions of patients are burdened with persistent symptoms and functional impairments. Cutaneous
Miriam Englander et al.
The British journal of ophthalmology, 97(4), 460-465 (2013-02-08)
To report the incidence rate of acute postoperative endophthalmitis secondary to therapeutic intravitreal injections. A retrospective review of all consecutive eyes after intravitreal injections was performed at the Massachusetts Eye and Ear Infirmary, Boston, from 1 January 2007 to 31
Brian C Gilger et al.
Investigative ophthalmology & visual science, 54(4), 2483-2492 (2013-03-28)
To evaluate the effect of triamcinolone acetonide (TA) administered into the suprachoroidal space (SCS) using a microneedle and compare it with intravitreal (IVT) TA injections in a porcine model of acute posterior segment inflammation. An IVT injection of balanced salt
Shivani Kasbekar et al.
Journal of cataract and refractive surgery, 39(3), 414-418 (2013-01-23)
To compare the clinical outcomes in patients who had triamcinolone acetate-assisted anterior vitrectomy and patients who had anterior vitrectomy without triamcinolone acetate after phacoemulsification complicated by posterior capsule rupture and vitreous loss. Arrowe Park Hospital, Wirral, United Kingdom. Retrospective consecutive
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