185205
Myristoyl chloride
97%
Synonyme(s) :
Tetradecanoyl chloride
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A propos de cet article
Formule linéaire :
CH3(CH2)12COCl
Numéro CAS:
Poids moléculaire :
246.82
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-994-6
Beilstein/REAXYS Number:
636924
MDL number:
Assay:
97%
Form:
liquid
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assay
97%
form
liquid
refractive index
n20/D 1.449 (lit.)
bp
250 °C/100 mmHg (lit.)
mp
−1 °C (lit.)
density
0.908 g/mL at 25 °C (lit.)
functional group
acyl chloride
SMILES string
CCCCCCCCCCCCCC(Cl)=O
InChI
1S/C14H27ClO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3
InChI key
LPWCRLGKYWVLHQ-UHFFFAOYSA-N
Application
Myristoyl chloride was used in the synthesis of 6-azafulleroid-6-deoxy-2,3-di-O-myristoylcellulose. It was used in N-acylation of chitosan to introduce hydrophobicity for use as matrix for drug delivery. It was used in the synthesis of semi-crystalline dendritic poly(ether-amide) derivatives.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
Classe de stockage
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Canh Le Tien et al.
Journal of controlled release : official journal of the Controlled Release Society, 93(1), 1-13 (2003-11-07)
N-acylation of chitosan with various fatty acid (C(6)-C(16)) chlorides increased its hydrophobic character and made important changes in its structural features. Unmodified chitosan exhibited a low degree of order (DO) and a weak tablet crushing strength. Chitosan acylated with a
Synthesis and crystallinity of dendritic poly (ether-amide) derivatives.
Wei H, et al.
Eur. Polymer J., 38(9), 1899-1905 (2002)
Diego Romano Perinelli et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 109, 93-102 (2016-10-04)
Toxicity is one of the main concerns limiting the use of surfactants. Many efforts have been devoted to the development of new amphiphilic molecules characterized by a lower toxicological profile and environmental impact. N-acyl amino acids are a class of