Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
Changer de vue
A propos de cet article
Formule empirique (notation de Hill) :
C65H132N2O17P2
Numéro CAS:
Poids moléculaire :
1275.69
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderdescription
1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (710332P-200mg), pkg of 1 × 25 mg (710332P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
General description
14:0 Cardiolipin or TMCL (1,1′,2,2′-tetramyristoyl cardiolipin) is a saturated CL and exists as gel at low temperatures.
Cardiolipin is an anionic phospholipid. The 14:0 indicates the fatty acyl substituents attached to the carbons of glycerol. It is localized to the inner mitochondrial membrane.
Application
14:0 Cardiolipin (ammonium salt) has been used as stable isotope-labeled standard prior to yeast strains high performance liquid chromatography electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS). It may be used as an internal standard in mass spectroscopy and in liposome preparation for electrophysiological studies.
14:0 Cardiolipin (ammonium salt) may be used in lipopeptide synthesis.
Biochem/physiol Actions
Cardiolipin participates in proton uptake pathway and also maintains the structure of enzymes involved. Cardiolipin maintains the mitochondrial function, membrane potential and structural support for the inner mitochondrial membrane and proteins in it. Concentration and composition changes of cardiolipin have been implicated in pathological conditions including ischemia, hypothyroidism, aging, heart failure and cardioskeletal myopathy.) Cardiolipin can form micelles/vesicles naturally.
TMCL (1,1′,2,2′-tetramyristoyl cardiolipin) bilayers are useful in generating multilamellar vesicles. Defects in the cardiolipin metabolic associated with Barth syndrome patients. Liposomes of TMCL with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and cholesterol are potential drug-delivery systems. TMCL displays temperature dependent thermotropic phase transitions.
Packaging
5 mL Amber Glass Screw Cap Vial (710332P-200mg)
5 mL Amber Glass Screw Cap Vial (710332P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Still not finding the right product?
Explore all of our products under 14:0 Cardiolipin (ammonium salt)
Classe de stockage
11 - Combustible Solids
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.