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A propos de cet article
Formule empirique (notation de Hill) :
C34H59N6O13P
Numéro CAS:
Poids moléculaire :
790.84
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Service technique
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Laissez-nous vous aiderNom du produit
16:0-06:0 NBD PS, Avanti Research™ - A Croda Brand 810192P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810192P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810192P
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylserine (PS) is a membrane phospholipid enriched in the cytosolic leaflet of plasma membrane. It comprises 2-10% of total phospholipids. NBD PS is a flurosently labelled phospholipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.
Application
16:0-06:0 NBD PS has been used as a labelled translocase to detect ATP-dependent translocation across late Golgi membranes. It is also suitable for analysis of phospholipid scramblase 1 (PLSCR1) scrambling in proteoliposomes and to determine enzyme specificity of lipoteichoic acid synthase enzyme (LtaS).
16:0-06:0 NBD PS or 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) has been used in the 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) − phospholipase (PL) translocation assay to characterize an ATP-dependent flippase activity in yeast Golgi membranes. It may be used: to detect vesicular stomatitis virus G (VSV G) protein mediated cell-cell fusion, measure the enzyme substrate specificity of lipoteichoic acid (LTA) synthase (LtaS), in liposomes to determine the role of phospholipid scramblase 1 (PLSCR1) in phospholipid scrambling.
Biochem/physiol Actions
Phosphatidylserine (PS) is involved in the regulation of many enzymes and structural components. It serves as an essential factor in the clearance of apoptotic cells. It is associated with cognitive disability in Alzheimer′s disease.
Packaging
5 mL Amber Glass Screw Cap Vial (810192P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Classe de stockage
11 - Combustible Solids
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