106425
N-Acetyl-L-cysteine
Mucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock.
Synonyme(s) :
N-Acetyl-L-cysteine, LNAC
Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
Changer de vue
A propos de cet article
Formule empirique (notation de Hill) :
C5H9NO3S
Numéro CAS:
Poids moléculaire :
163.19
UNSPSC Code:
12352209
NACRES:
NA.25
MDL number:
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderdescription
Merck USA index - 14, 88
Quality Level
assay
≥98% (titration)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
water: 50 mg/mL
anion traces
chloride (Cl-): ≤0.04%, sulfate (SO42-): ≤0.03%
cation traces
Fe: ≤20 ppm
shipped in
ambient
storage temp.
15-25°C
SMILES string
SCC(NC(=O)C)C(=O)O
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)
InChI key
PWKSKIMOESPYIA-UHFFFAOYSA-N
General description
A mucolytic agent and thio-based antioxidant. Increases the cellular pool of free-radical scavengers. Inhibits HIV replication. Prevents apoptotic death of neuronal cells. Antidote for acetaminophen poisoning. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
Mucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock. Increases cellular pools of free-radical scavengers. Inhibitor of HIV replication. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
Application
- Chlorpyrifos-induced suppression of the antioxidative defense system leads to cytotoxicity and genotoxicity in macrophages.: The study highlights the protective role of N-acetyl-L-cysteine against chlorpyrifos-induced oxidative damage in macrophages, emphasizing its importance in mitigating pesticide toxicity (Lu et al., 2024).
- N-Acetyl-L-Cysteine Attenuates Titanium Dioxide Nanoparticle (TiO2 NP)-Induced Autophagy in Male Germ Cells.: This research explores how N-acetyl-L-cysteine can mitigate the autophagic effects induced by titanium dioxide nanoparticles in male germ cells, suggesting its use in reproductive health (Shin et al., 2024).
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
Other Notes
Ortolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
Ferrari, G., et al. 1995. J. Neurosci.15, 2857.
Weinander, R., et al. 1994. J. Biol. Chem.269, 71.
Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
Ferrari, G., et al. 1995. J. Neurosci.15, 2857.
Weinander, R., et al. 1994. J. Biol. Chem.269, 71.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Classe de stockage
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.