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Merck

27227

Acétate d′éthyle

puriss., meets analytical specification of Ph. Eur., BP, NF, ≥99.5% (GC)

Synonyme(s) :

EtOAc

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A propos de cet article

Formule linéaire :
CH3COOC2H5
Numéro CAS:
Poids moléculaire :
88.11
UNSPSC Code:
12352108
NACRES:
NB.11
PubChem Substance ID:
EC Number:
205-500-4
Beilstein/REAXYS Number:
506104
MDL number:
Assay:
≥99.5% (GC)
Technique(s):
GC/GC: suitable
Bp:
76.5-77.5 °C (lit.)
Vapor pressure:
73 mmHg ( 20 °C)
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vapor density

3 (20 °C, vs air)

Quality Segment

vapor pressure

73 mmHg ( 20 °C)

grade

puriss.

assay

≥99.5% (GC)

form

liquid

autoignition temp.

801 °F

quality

meets analytical specification of Ph. Eur., BP, NF

expl. lim.

2.2-11.5 %, 38 °F

technique(s)

GC/GC: suitable

impurities

residual solvents, complies, ≤0.003% non-volatile matter, ≤0.005% free acid (as CH3COOH), ≤0.01% methyl. comp.(as acetic acid methylester), ≤0.1% ethanol (GC), ≤0.1% water (Karl Fischer), ≤0.2% related subst. (GC)

refractive index

n20/D 1.371-1.373, n20/D 1.3720 (lit.)

bp

76.5-77.5 °C (lit.)

mp

−84 °C (lit.)

density

0.898-0.902 g/mL at 20 °C, 0.894-0.898 g/mL at 25 °C, 0.902 g/mL at 25 °C (lit.)

suitability

complies for appearance of solution, complies for reaction against H2SO4, corresponds for chromatography, passes test for identity (IR)

SMILES string

CCOC(C)=O

format

neat

InChI

1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3

InChI key

XEKOWRVHYACXOJ-UHFFFAOYSA-N

Application


  • [Determination of 12 prohibited veterinary drug residues in pig urine by ultra high performance liquid chromatography-tandem mass spectrometry]: Ethyl acetate is utilized for sample preparation in this advanced method to detect drug residues in animal samples, emphasizing its role in veterinary pharmaceutical compliance (Wan et al., 2024).

  • Therapeutic effect of Ginkgetin on smoke-induced airway inflammation by down-regulating the c/EBPβ signaling pathway and CCL2 expression: This study explores the anti-inflammatory properties of Ginkgetin, where ethyl acetate is used in the extraction process, highlighting its utility in biomedical research (Tao et al., 2024).

  • Effect of methanol extract of Plectranthus esculentus N.E.Br tuber and its fractions on indices of benign prostatic hyperplasia in Wistar rats: Ethyl acetate is employed in the extraction of bioactive compounds for pharmacological studies, showing its critical role in therapeutic applications (Kanu et al., 2024).

  • Phytochemical evaluation of Ziziphus mucronata and Xysmalobium undulutum towards the discovery and development of anti-malarial drugs: Demonstrates the use of ethyl acetate in phytochemical screenings, contributing to the development of new anti-malarial medications (Buthelezi et al., 2024).

  • The First Records of the In Silico Antiviral and Antibacterial Actions of Molecules Detected in Extracts of Algerian Fir (Abies numidica De Lannoy) Using LC-MS/MS Analysis: This research utilizes ethyl acetate for extracting compounds from plants for antiviral and antibacterial testing, underscoring its importance in the study of natural products (Benouchenne et al., 2024).

Other Notes

The article number 27227-4X2.5L-M will be discontinued. Please order the single bottle 27227-2.5L-M which is physically identical with the same exact specifications.
The article number 27227-4X2.5L-R will be discontinued. Please order the single bottle 27227-2.5L-R which is physically identical with the same exact specifications.


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pictograms

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Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Classe de stockage

3 - Flammable liquids

wgk

WGK 1

flash_point_f

24.8 °F - closed cup

flash_point_c

-4 °C - closed cup



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