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agency
suitable for ASTM® 7969, suitable for ASTM® 7979, suitable for DIN 38407-43, suitable for EPA 1634, suitable for EPA 534, suitable for EPA 8328, suitable for EPA ACB B21-03, suitable for ISO 21675 2019, suitable for ISO 25101, suitable for ISO/CEN 15968-2011
vapor density
2.07 (vs air)
assay
≥99.99% trace metals basis
form
liquid
autoignition temp.
800 °F
expl. lim.
16 %, 92 °F, 4 %, 59 °F
technique(s)
HPLC: suitable
refractive index
n
pH
2.5 (20 °C, 50 g/L)
bp
117-118 °C (lit.)
mp
16.2 °C (lit.)
density
1.04 g/mL at 25 °C (lit.)
SMILES string
[F2C(F2C)13F3C]C(O)=O
InChI
1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
InChI key
QTBSBXVTEAMEQO-UHFFFAOYSA-N
Application
- For the solvent-free one-pot condensation of indoles with aryl or heteroaryl aldehydes to synthesize di(indolyl)methanes.
- In the Pictet-Spengler reaction of substituted tryptamines with cyclic ketones to synthesize tetrahydrospiro-Ͱ-carbolines.
- To synthesize trisubstituted thiazoles via domino multicomponent reaction.
It can also be used as a:
- solvent to synthesize aryl amine-functionalized 1,3,5-triazine derivatives via aryl amination of cyanuric chloride with aromatic amines.
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Mot-clé
Danger
Codes de danger
Mentions de précaution
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A
Classe de stockage
3 - Flammable liquids
Point d'éclair (°F)
102.2 °F - closed cup
Point d'éclair (°C)
39 °C - closed cup
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