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Merck

366927

Chloroforme

suitable for HPLC, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

Synonyme(s) :

Trichlorométhane, Trichlorure de méthylidyne

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A propos de cet article

Formule empirique (notation de Hill) :
CHCl3
Numéro CAS:
67-66-3
Poids moléculaire :
119.38
UNSPSC Code:
12190000
NACRES:
NA.04
PubChem Substance ID:
329755457
MDL number:
MFCD00000826
Beilstein/REAXYS Number:
1731042
Grade:
HPLC grade
Assay:
≥99.8%
Technique(s):
HPLC: suitable
Bp:
60.5-61.5 °C (lit.)
Vapor pressure:
160 mmHg ( 20 °C)

Principaux documents

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Nom du produit

Chloroforme, suitable for HPLC, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

InChI

1S/CHCl3/c2-1(3)4/h1H

SMILES string

ClC(Cl)Cl

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

grade

HPLC grade

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

assay

≥99.8%

form

liquid

purified by

glass distillation

contains

0.5-1.0% ethanol as stabilizer

technique(s)

HPLC: suitable

impurities

Acetone and aldehyde, passes test
 Acid and chloride, passes test
 Free chlorine (Cl), passes test
 H2SO4, passes test (darkened)
≤0.01% water

evapn. residue

<0.0003%

color

APHA: ≤10

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C (lit.)

mp

−63 °C (lit.)

density

1.48 g/mL at 25 °C
1.492 g/mL at 25 °C (lit.)

cation traces

Pb: ≤0.05 ppm

λ

H2O reference

UV absorption

λ: 245 nm Amax: 1.00
λ: 255 nm Amax: 0.15
λ: 260 nm Amax: 0.15
λ: 270 nm Amax: 0.02
λ: 290 nm Amax: 0.01
λ: 400 nm Amax: 0.01

suitability

passes test for HPLC

storage temp.

room temp

Quality Level

100

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Catégories apparentées

Application


  • Novel Approaches for the Analysis and Isolation of Benzylisoquinoline Alkaloids in Chelidonium majus.: This study presents innovative methodologies using chloroform in the extraction and analysis processes, highlighting advances in alkaloid chemistry (Ganzera et al., 2024).

  • Antioxidant, anti-amylase, anti-lipase, and efficiency of Satureja fatty acid on the anti-inflammatory parameters in lipopolysaccharide-stimulated macrophage through Nrf2/NF-kB/NADH oxidase pathway.: Although primarily focused on biological assays, this paper includes essential methodologies employing chloroform for the extraction and purification of biochemical compounds (Saharkhiz MJ et al., 2024).

  • Recent additions and access to a multidimensional lipidomic database containing liquid chromatography, ion mobility spectrometry, and tandem mass spectrometry information.: Chloroform is utilized as a key solvent in the extraction and analysis processes within lipidomics, demonstrating its critical role in modern analytical techniques (Baker ES et al., 2024).

  • Preparation and optimization of dummy molecularly imprinted polymer-based solid-phase extraction system for selective enrichment of p-toluene sulfonate esters genotoxic impurities.: The study includes the use of chloroform in the preparation of polymers for advanced chromatographic applications, illustrating its versatility in analytical methodologies (Shan G et al., 2024).



Other Notes

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Packaging

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Certificats d'analyse (COA)

Lot/Batch Number
SHBT4118
SHBS7995
SHBT0753
SHBT0139
SHBS7762

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Radovan Spurny et al.
The Journal of biological chemistry, 288(12), 8355-8364 (2013-02-01)
Pentameric ligand-gated ion channels (pLGICs), such as nicotinic acetylcholine, glycine, γ-aminobutyric acid GABA(A/C) receptors, and the Gloeobacter violaceus ligand-gated ion channel (GLIC), are receptors that contain multiple allosteric binding sites for a variety of therapeutics, including general anesthetics. Here, we
Philip Jermann et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(33), E3415-E3421 (2014-08-06)
Trimethylation of histone H3 at lysine 27 (H3K27me3) is a chromatin mark associated with Polycomb-mediated gene repression. Despite its critical role in development, it remains largely unclear how this mark is targeted to defined loci in mammalian cells. Here, we
Kuan Sun et al.
Nature communications, 6, 6013-6013 (2015-01-15)
Solution-processed organic photovoltaic cells (OPVs) hold great promise to enable roll-to-roll printing of environmentally friendly, mechanically flexible and cost-effective photovoltaic devices. Nevertheless, many high-performing systems show best power conversion efficiencies (PCEs) with a thin active layer (thickness is ~100 nm) that
Mette Bohl et al.
The American journal of clinical nutrition, 101(4), 870-878 (2015-04-04)
Abdominal obesity and exaggerated postprandial lipemia are independent risk factors for cardiovascular disease (CVD) and mortality, and both are affected by dietary behavior. We investigated whether dietary supplementation with whey protein and medium-chain saturated fatty acids (MC-SFAs) improved postprandial lipid
Juyao Dong et al.
ACS nano, 8(5), 5199-5207 (2014-05-02)
The temperature increase inside mesoporous silica nanoparticles induced by encapsulated smaller superparamagnetic nanocrystals in an oscillating magnetic field is measured using a crystalline optical nanothermometer. The detection mechanism is based on the temperature-dependent intensity ratio of two luminescence bands in
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