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Merck

75746

Dodécylsulfate de sodium

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≥99.0% (GC), dust-free pellets

Synonyme(s) :

Dodécyl sulfate sodium salt, Dodécylsulfate de sodium, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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About This Item

Formule linéaire :
CH3(CH2)11OSO3Na
Numéro CAS:
151-21-3
Poids moléculaire :
288.38
NACRES:
NA.25
PubChem Substance ID:
329766677
eCl@ss:
39093306
UNSPSC Code:
12161900
EC Number:
205-788-1
MDL number:
MFCD00036175
Beilstein/REAXYS Number:
3599286

Nom du produit

Dodécylsulfate de sodium, ≥99.0% (GC), dust-free pellets

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

description

anionic

assay

≥99.0% (GC)

form

rod

mol wt

average mol wt 18,000

Quality Level

200

greener alternative product characteristics

Catalysis
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aggregation number

62

loss

≤5% loss on drying

CMC

7-10 (lit.)

mp

204 - 207  °C (399 - 405 °F)
204-207 °C (lit.)

transition temp

cloud point >100 °C(lit.)

solubility

H2O: soluble 0.29 gm in 10ml, clear, colorless
H2O: 0.1 M at 20 °C, clear, colorless
 130 g/L at 20 °C (68 °F)

density

1 g/cm3

anion traces

chloride (Cl-): ≤200 mg/kg

cation traces

Ca: ≤25 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
K: ≤200 mg/kg
Mg: ≤20 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

HLB

40(lit.)

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Catégories apparentées

Application

Détergent anionique
Sodium dodecyl sulfate (SDS) has been used:
  • as a negatively charged surfactant to study its effects on filtration flux and membrane fouling during the microfiltration of the surfactant-stabilized oil emulsion
  • as a component of plant extraction buffer, and transferring buffer for western blot
  • as a component of 5× Laemmli sample buffer (5× LB) and 10× SDS running buffer for sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblot

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS) effectively binds to the positively charged and the hydrophobic residues of proteins via sulfate groups and alkyl chains. It functions as a vital detergent in the domain of structural biology and protein folding/unfolding studies. SDS can stimulate the creation of α-helices in a protein structure. It has the ability to promote cooperative unfolding in several proteins including bovine serum albumin (BSA), β-lactoglobulin, α-lactalbumin, and hen egg-white lysozyme structures at elevated concentrations. 

Features and Benefits

  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
  • Tested for trace levels of Anions and Cations
  • High-purity product ideal for biochemical research purposes

General description

Sodium dodecyl sulfate (SDS) is an organic sodium salt used as both a detergent and a protein denaturant in biochemical research. Its unique structure includes a long-chain aliphatic group with a negatively charged sulfate, making it an effective agent for denaturing proteins. This property is especially valuable in electrophoresis, a technique used to separate and analyze macromolecules like proteins. SDS, with its negative charge, interacts with proteins and lipids to create micellar structures, aiding in solubilizing and stabilizing these biomolecules.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is used as a surfactant to enhance catalysis.  Click here for more information.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Classe de stockage

11 - Combustible Solids

wgk

WGK 2

flash_point_f

338.0 °F

flash_point_c

170 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificats d'analyse (COA)

Lot/Batch Number
BCCP0540
BCCP0429
SDBB4562
SDBB4560
SDBB3638

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

J Kamerbeek et al.
Journal of clinical microbiology, 35(4), 907-914 (1997-04-01)
Widespread use of DNA restriction fragment length polymorphism (RFLP) to differentiate strains of Mycobacterium tuberculosis to monitor the transmission of tuberculosis has been hampered by the need to culture this slow-growing organism and by the level of technical sophistication needed
D Wessel et al.
Analytical biochemistry, 138(1), 141-143 (1984-04-01)
A rapid method based on a defined methanol-chloroform-water mixture for the quantitative precipitation of soluble as well as hydrophobic proteins from dilute solutions (e.g., column chromatography effluents) has been developed. The effectiveness of this method is not affected by the
K Fujimoto
Journal of cell science, 108 ( Pt 11), 3443-3449 (1995-11-01)
We propose a new electron microscopic method, the sodium dodecylsulphate (SDS)-digested freeze-fracture replica labeling technique, to study the two-dimensional distribution of integral membrane proteins in cellular membranes. Unfixed tissue slices were frozen with liquid helium, freeze-fractured, and replicated in a
The gross conformation of protein-sodium dodecyl sulfate complexes.
J A Reynolds et al.
The Journal of biological chemistry, 245(19), 5161-5165 (1970-10-10)
Kazuya Ishikawa et al.
Nature communications, 5, 5430-5430 (2014-11-13)
Pathogen effector proteins are delivered to host cells to suppress plant immunity. However, the mechanisms by which effector proteins function are largely unknown. Here we show that expression of XopP(Xoo), an effector of rice pathogen Xanthomonas oryzae pv. oryzae, in
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