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Merck

C7559

Chloroforme

≥99%, PCR Reagent, contains amylenes as stabilizer

Synonyme(s) :

Trichlorométhane, Trichlorure de méthylidyne

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About This Item

Formule empirique (notation de Hill) :
CHCl3
Numéro CAS:
Poids moléculaire :
119.38
UNSPSC Code:
12191502
NACRES:
NA.28
PubChem Substance ID:
EC Number:
200-663-8
Beilstein/REAXYS Number:
1731042
MDL number:
assay:
≥99%
technique(s):
PCR: suitable
bp:
60.5-61.5 °C (lit.)
vapor pressure:
160 mmHg ( 20 °C)

Nom du produit

Chloroforme, ≥99%, PCR Reagent, contains amylenes as stabilizer

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

InChI

1S/CHCl3/c2-1(3)4/h1H

SMILES string

ClC(Cl)Cl

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

assay

≥99%

form

liquid

contains

amylenes as stabilizer

packaging

vial of 1.5 mL

technique(s)

PCR: suitable

color

colorless

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C (lit.)

mp

−63 °C (lit.)

density

1.492 g/mL at 25 °C (lit.)

foreign activity

DNase, RNase, none detected

Quality Level

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Application

Chloroform has been used in phenol-chloroform extraction to find its ability to purify nucleic acids from blood culture fluids. It has also been used in RNA extraction/isolation and purification.

General description

Chloroform is used in pharmaceutical preparations as an anesthetic and as an additive. It is now mainly used as an organic solvent. Chloroform is produced by anthropogenic and natural sources. This abundant halocarbon in the atmosphere is found in ground and surface water sources.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

ppe

Eyeshields, Faceshields, Gloves


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Consulter la Bibliothèque de documents

Kidney
Encyclopedia of Toxicology (2014)
Accalia Fu et al.
Diabetologia, 58(7), 1513-1522 (2015-04-16)
Precise regulation of insulin secretion by the pancreatic beta cell is essential for the maintenance of glucose homeostasis. Insulin secretory activity is initiated by the stepwise breakdown of ambient glucose to increase cellular ATP via glycolysis and mitochondrial respiration. Knockout
Pramod Kumar et al.
Tissue engineering. Part C, Methods, 21(7), 660-670 (2014-12-24)
Tissue engineering by self-assembly uses the cells' secretome as a regeneration template and biological factory of trophic factors. Despite the several advantages that have been witnessed in preclinical and clinical settings, the major obstacle for wide acceptance of this technology
Kuan Sun et al.
Nature communications, 6, 6013-6013 (2015-01-15)
Solution-processed organic photovoltaic cells (OPVs) hold great promise to enable roll-to-roll printing of environmentally friendly, mechanically flexible and cost-effective photovoltaic devices. Nevertheless, many high-performing systems show best power conversion efficiencies (PCEs) with a thin active layer (thickness is ~100 nm) that
Mette Bohl et al.
The American journal of clinical nutrition, 101(4), 870-878 (2015-04-04)
Abdominal obesity and exaggerated postprandial lipemia are independent risk factors for cardiovascular disease (CVD) and mortality, and both are affected by dietary behavior. We investigated whether dietary supplementation with whey protein and medium-chain saturated fatty acids (MC-SFAs) improved postprandial lipid

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