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G0299

Protodioscin

Name: Protodioscin
Brand: SIGMA

from Dioscorea spp., ≥98% (HPLC)

Synonyme(s) :

Furostanol I

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A propos de cet article

Formule empirique (notation de Hill) :

C₅₁H₈₄O₂₂

Numéro CAS:

55056-80-9

Poids moléculaire :

1049.20

MDL number:

MFCD03427682

UNSPSC Code:

12352212

NACRES:

NA.25

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Propriétés

biological source

Dioscorea spp.

Quality Segment

200

assay

≥98% (HPLC)

form

powder

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

O1[C@H]([C@@H]([C@@H]([C@H]([C@@H]1C)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O[C@@H]9O[C@H]([C@@H]([C@H]([C@H]9O)O)O)C)CO)O[C@H]3CC[C@@]4([C@@H]5[C@H]([C@H]6[C@@]([C@@H]7[C@@H](O[C@]([C@H]7C)(O)CC[C@H](CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C)C6)

InChI

1S/C51H84O22/c1-20(19-65-45-39(60)38(59)35(56)30(17-52)69-45)9-14-51(64)21(2)32-29(73-51)16-28-26-8-7-24-15-25(10-12-49(24,5)27(26)11-13-50(28,32)6)68-48-44(72-47-41(62)37(58)34(55)23(4)67-47)42(63)43(31(18-53)70-48)71-46-40(61)36(57)33(54)22(3)66-46/h7,20-23,25-48,52-64H,8-19H2,1-6H3/t20-,21+,22+,23+,25+,26-,27+,28+,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39-,40-,41-,42+,43-,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1

InChI key

LVTJOONKWUXEFR-UEZXSUPNSA-N

Description

General description

Protodioscin is a steroidal saponin found in a variety of plant species. It consists of aglycone and glycone moieties and occurs as an active ingredient of the herbal aphrodisiac Tribulus terrestris used in traditional Chinese and Indian medicine.

Application

Protodioscin has been used to study the inhibitory effect of fenugreek and quinoa extracts on the activity of α-amylase and pancreatic lipase under in vitro traditional conditions. It has also been used as a standard in the study to carry out the structural characterization of the steroidal saponins extracted from Smilax trinervula.

Biochem/physiol Actions

Protodioscin shows a notable inhibitory effect on digestive enzymes such as α-amylase and pancreatic lipase. It is posited to increase the levels of testosterone, luteinizing hormone, dehydroepiandrosterone, dihydrotestosterone, and dehydroepiandrosterone sulfate along with improving libido and spermatogenesis in humans and animals. It exhibits anti-tumor activity especially against leukemia, colon cancer, and prostate cancer.

Saponin phytochemical found in asparagus. Cardioprotective and anti-hyperlipidemic agent. Cytotoxic effect against human cancer cell lines.

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Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c