L9650
Lithium chloride
Molecular Biology, ≥99%
Synonyme(s) :
LiCl
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A propos de cet article
Formule linéaire :
LiCl
Numéro CAS:
Poids moléculaire :
42.39
NACRES:
NA.31
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-212-3
MDL number:
Assay:
≥99%
Grade:
Molecular Biology
Form:
powder
Solubility:
H2O: 100 mg/mL at 20 °C, clear, colorless
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Molecular Biology
Quality Level
assay
≥99%
form
powder
mp
605 °C (lit.)
solubility
H2O: 100 mg/mL at 20 °C, clear, colorless
anion traces
sulfate (SO42-): ≤0.01%
cation traces
Ba: ≤0.003%, Fe: ≤0.001%, K: ≤0.01%, Na: ≤0.20%, heavy metals (as Pb): ≤0.002%
foreign activity
DNase, NICKase, RNase, protease, none detected
SMILES string
[Li+].[Cl-]
InChI
1S/ClH.Li/h1H;/q;+1/p-1
InChI key
KWGKDLIKAYFUFQ-UHFFFAOYSA-M
Application
May be used to selectively precipitate RNA.
Lithium chloride has been used:
- in the preparation of wash buffer for chromatin immunoprecipitation
- in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
- to treat aged myoblast as glycogen synthase kinase (GSK) inhibitor to analyse its effect on wingless/tailess (wnt) signaling
Biochem/physiol Actions
Lithium chloride has the ability to block glycogen synthase kinase (GSK). It may also possess anti-inflammatory effects at low and non-toxic concentrations.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
Classe de stockage
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Molecules to Medicine with mTOR, 317-329 (2016)
Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts
Vertino AM, et al.
Molecular Biology of the Cell, 16(4), 2039-2048 (2005)