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A propos de cet article
Formule linéaire :
CH3SO3CH2CH3
Numéro CAS:
Poids moléculaire :
124.16
UNSPSC Code:
12352108
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-536-7
Beilstein/REAXYS Number:
773969
MDL number:
Form:
liquid
Quality level:
Service technique
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liquid
Quality Level
refractive index
n20/D 1.418 (lit.)
bp
85-86 °C/10 mmHg (lit.)
density
1.206 g/mL at 20 °C
SMILES string
CCOS(C)(=O)=O
InChI
1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3
InChI key
PLUBXMRUUVWRLT-UHFFFAOYSA-N
Application
Ethyl methanesulfonate had been used for inducing mutation in mouse embryonic fibroblasts, yeast human embryonic kidney cell lines and human lymphocytes.
Biochem/physiol Actions
Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1
Classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
212.0 °F
flash_point_c
100 °C
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Contenu apparenté
Kade M Power et al.
PLoS genetics, 16(10), e1009052-e1009052 (2020-10-17)
Ciliary microtubules are subject to post-translational modifications that act as a "Tubulin Code" to regulate motor traffic, binding proteins and stability. In humans, loss of CCP1, a cytosolic carboxypeptidase and tubulin deglutamylating enzyme, causes infantile-onset neurodegeneration. In C. elegans, mutations
Jinzhu Li et al.
Genes, 11(11) (2020-10-30)
Lateral root development is a complex process regulated by numerous factors. An important role for sugar in lateral root development has been known for a while, but the underlying molecular basis still remains unclear. In this study, we first showed
Genotoxicity Effect of Ethyl Methanesulfonate on Root Tip Cells of Chilli (Capsicum annuum L.)
Devi AS and Mullainathan L
World Journal of Agricultural Sciences, 7(4), 368-374 (2011)

