M6020
D-(+)-Mannose
powder, BioReagent, suitable for cell culture
Synonyme(s) :
D-Mannopyranose
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A propos de cet article
Formule empirique (notation de Hill) :
C6H12O6
Numéro CAS:
Poids moléculaire :
180.16
UNSPSC Code:
12352201
NACRES:
NA.75
PubChem Substance ID:
EC Number:
222-392-4
Beilstein/REAXYS Number:
1564373
MDL number:
Service technique
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Laissez-nous vous aiderbiological source
plant (Spruce, Birch or Beech Wood, Glucose)
Quality Level
product line
BioReagent
assay
≥99%
form
powder
technique(s)
cell culture | mammalian: suitable
mp
133-140 °C (lit.)
solubility
H2O: 50 mg/mL
application(s)
advanced drug delivery
agriculture
SMILES string
OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1
InChI key
WQZGKKKJIJFFOK-QTVWNMPRSA-N
General description
Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration. Majority of mannose is synthesised from its epimer glucose. It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.
Application
Mannose is an aldohexose carbohydrate. This product may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation.
D-(+)-Mannose has been used:
- as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa
- as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
- in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines
Biochem/physiol Actions
Mannose may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation. cis-Golgi glycoproteins have high mannose and are prone to Endoglycosidase H or peptide N-glycosidase (N-glycanase) digestion.
Classe de stockage
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Metabolic manipulation of glycosylation disorders in humans and animal models
Freeze HH and Sharma V
Seminars in Cell & Developmental Biology, 21(6), 655-662 (2010)
M J Carlino et al.
Gut microbes, 12(1), 1-21 (2020-11-03)
Infectious diarrhea causes approximately 179 million illnesses annually in the US. Multiplex PCR assays for enteric pathogens detect enteropathogenic Escherichia coli (EPEC) in 12-29% of diarrheal stool samples from all age groups in developed nations. The aim of this study
Agrobacterium-mediated transformation of Sorghum bicolor using immature embryos
Transgenic Plants, 109-122 (2012)