Accéder au contenu
Merck

N3014

β-Nicotinamide-adénine-dinucléotide hydrate

greener alternative

suitable for cell culture, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast

Synonyme(s) :

β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucléotide, NAD, Nadide

Se connecter pour consulter les tarifs organisationnels et contractuels.

Sélectionner une taille de conditionnement

A propos de cet article

Formule empirique (notation de Hill) :
C21H27N7O14P2 · xH2O
Numéro CAS:
53-84-9
Poids moléculaire :
663.43 (anhydrous basis)
UNSPSC Code:
41106305
eCl@ss:
39200202
PubChem Substance ID:
24897613
NACRES:
NA.55
MDL number:
MFCD00036253

Principaux documents

Voir toute la documentation
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider

Nom du produit

β-Nicotinamide-adénine-dinucléotide hydrate, suitable for cell culture, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast

SMILES string

NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

biological source

yeast

assay

≥96.5% (HPLC)
≥96.5% (spectrophotometric assay)

form

powder

mol wt

Mw 663.43 g/mol

Quality Level

200

Gene Information

human ... ESR1(2099), ESR2(2100)

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

cell culture | mammalian: suitable

impurities

≤3% Acetone

color

white to off-white

solubility

H2O: 50 mg/mL

greener alternative category

DfS-Developed

storage temp.

−20°C

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Catégories apparentées

Biochem/physiol Actions

Accepteur d'électrons

Other Notes

Il s′agit de la forme courante du NAD.
Meets or exceeds NRC specifications.

Packaging

Produit conditionné en fonction du poids solide.

Application


  • Spectroelectrochemical Enzyme Sensor System for Acetaldehyde Detection in Wine.: This study explores the development of a novel sensor system using β-Nicotinamide adenine dinucleotide hydrate to detect acetaldehyde in wine, enhancing the accuracy of wine quality control (Ibáñez et al., 2022).

  • Screening of Lactate Dehydrogenase Inhibitor from Bioactive Compounds in Natural Products by Electrophoretically Mediated Microanalysis.: The research utilizes β-Nicotinamide adenine dinucleotide hydrate to screen potential lactate dehydrogenase inhibitors, which could lead to new therapeutic agents for diseases such as cancer (Li et al., 2021).

  • Combination of NAD(+) and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress.: This research highlights the neuroprotective effects of NAD+ and NADPH in stroke models, emphasizing the potential therapeutic applications of β-Nicotinamide adenine dinucleotide hydrate in neuroprotection (Huang et al., 2018).

General description

We are committed to bringing you Greener Alternative Products that adhere to one or more of the 12 Principles of Green Chemistry. Beta-Nicotinamide adenine dinucleotide is a bio-derived redox cofactor that works together with enzymes as part of a biocatalyst system. It can be efficiently recycled in many reactions, enabling selective oxidations while reducing waste and supporting greener, more sustainable chemical processes. Click here for more information.

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
0000508488
0000508488
0000464243
0000464242
0000464247

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Rechercher un(e) COA

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Jeerus Sucharitakul et al.
The Journal of biological chemistry, 288(49), 35210-35221 (2013-10-17)
3-Hydroxybenzoate 6-hydroxylase (3HB6H) from Rhodococcus jostii RHA1 is an NADH-specific flavoprotein monooxygenase that catalyzes the para-hydroxylation of 3-hydroxybenzoate (3HB) to form 2,5-dihydroxybenzoate (2,5-DHB). Based on results from stopped-flow spectrophotometry, the reduced enzyme-3HB complex reacts with oxygen to form a C4a-peroxy
Christian Dölle et al.
The FEBS journal, 280(15), 3530-3541 (2013-04-27)
Mitochondrial metabolism is intimately connected to the universal coenzyme NAD. In addition to its role in redox reactions of energy transduction, NAD serves as substrate in regulatory reactions that lead to its degradation. Importantly, all types of the known NAD-consuming
Ana P Gomes et al.
Cell, 155(7), 1624-1638 (2013-12-24)
Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but
Brian J North et al.
The EMBO journal, 33(13), 1438-1453 (2014-05-16)
Mice overexpressing the mitotic checkpoint kinase gene BubR1 live longer, whereas mice hypomorphic for BubR1 (BubR1(H/H)) live shorter and show signs of accelerated aging. As wild-type mice age, BubR1 levels decline in many tissues, a process that is proposed to
Anna Ferretta et al.
Biochimica et biophysica acta, 1842(7), 902-915 (2014-03-04)
Mitochondrial dysfunction and oxidative stress occur in Parkinson's disease (PD), but the molecular mechanisms controlling these events are not completely understood. Peroxisome proliferator-activated receptor-gamma coactivator-1α (PGC-1α) is a transcriptional coactivator known as master regulator of mitochondrial functions and oxidative metabolism.
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique