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Merck

P9625

Phenazine methosulfate

powder, electron acceptor

Synonyme(s) :

5-Methylphenazinium methyl sulfate, N-Methylphenazonium methyl sulfate, PMS

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About This Item

Formule linéaire :
C13H11N2 · CH3SO4
Numéro CAS:
299-11-6
Poids moléculaire :
306.34
NACRES:
NA.77
PubChem Substance ID:
24899045
UNSPSC Code:
12352200
EC Number:
206-072-1
MDL number:
MFCD00011923
Beilstein/REAXYS Number:
3898869

Nom du produit

Phenazine methosulfate,

InChI key

RXGJTUSBYWCRBK-UHFFFAOYSA-M

InChI

1S/C13H11N2.CH4O4S/c1-15-12-8-4-2-6-10(12)14-11-7-3-5-9-13(11)15;1-5-6(2,3)4/h2-9H,1H3;1H3,(H,2,3,4)/q+1;/p-1

SMILES string

COS([O-])(=O)=O.C[n+]1c2ccccc2nc3ccccc13

form

powder

λ

0.01 g/L in H2O, 1 cm path

UV absorption

λ: 387.5 nm Amax

antibiotic activity spectrum

fungi

mode of action

DNA synthesis | interferes
cell membrane | interferes

storage temp.

−20°C

Quality Level

200

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Catégories apparentées

Application

Phenazine methosulfate is used with ascorbic acid to determine nitric oxide reductase activity.
Phenazine methosulfate has been used:
  • as a component of succinate dehydrogenase enzyme substrate solution
  • to induce superoxide radical generation in red blood cell suspensions and to study its influence on RBC deformability
  • as a component of complex II histochemistry media

Biochem/physiol Actions

Phenazine m ethosulfate (PMS) acts as a good electron acceptor. PMS is reduced non-enzymatically by (nicotinamide adenine dinucleotide) NADH and (nicotinamide adenine dinucleotide phosphate) NADPH.

General description

Phenazines are heterocyclic compounds produced as secondary metabolites by bacteria.

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
0000504481
0000504480
0000504480
0000504481
0000463313

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Consulter la Bibliothèque de documents

Ángela Inmaculada López-Lorente et al.
Materials science & engineering. C, Materials for biological applications, 103, 109805-109805 (2019-07-28)
In recent years, both nanotechnology and the use of nanomaterials have been growing in fields as diverse as biomedicine, food or electronics. Particularly metal nanoparticles, such as gold nanoparticles (AuNPs), are being widely studied with different applications, for example as
Handbook on Clostridia, , pages=, 84-84 (2005)
Junji Zhang et al.
Nature communications, 8(1), 987-987 (2017-10-19)
Development of powerful fluorescence imaging probes and techniques sets the basis for the spatiotemporal tracking of cells at different physiological and pathological stages. While current imaging approaches rely on passive probe-analyte interactions, here we develop photochromic fluorescent glycoprobes capable of
Ludmila Yarmolinsky et al.
Rejuvenation research, 22(4), 282-288 (2018-10-26)
Crude ethanolic extracts from Phlomis viscosa Poiret leaves from the Judea region (Israel) are renowned for their remarkable geroprotective properties: anti-inflammatory, anti-diabetic, and anti-cancer. A phytochemical investigation carried out in this study revealed that the tested plant might belong to
Duong Luong et al.
Materials science & engineering. C, Materials for biological applications, 103, 109759-109759 (2019-07-28)
Transition metals (TM) are essential microelements with various biological functions demanded in tissue regeneration applications. Little is known about therapeutic potential of TM within soft hydrogel biomaterials. The soluble divalent TM, such as Zn, Cu, Mn and Co, were stably
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