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References


[1] Liu D, Ren T, Gao X. Cationic Transfection Lipids, Current Medicinal Chemistry. 2003; 10(14): 1307‐1315

[2] Wattiaux R, Jadot M, Warnier‐Pirotte MT, Wattiaux‐De Coninck S. Cationic Lipids Destabilize Lysosomal Membrane in vitro. FEBS Letter. 1997; 417(2): 199‐202

[3] Xu Y, Szoka FC. Mechanism of DNA Release from Cationic Liposome/DNA Complexes used in Cell Transfection. Biochemistry. 1996; 35(18): 5616‐5623

[4] Felgner JH, Kumar R, Sridhar CN, Wheeler CJ, Tsai YJ, Border R, Ramsey P, Martin M, Felgner PL. Enhanced Gene Delivery and Mechanism Studies with a Novel Series of Cationic Lipid Formulations. J. Biol. Chem. 1994; 269(4): 2550‐2561

[5] Heyes JA, Niculescu‐Duvaz D, Cooper RG, Springer CJ. Synthesis of Novel Cationic Lipids: Effect of Structural Modification on the Efficiency of Gene Transfer. J. Med. Chem. 2002; 45(1): 99‐114

[6] Hirko A, Tang F, Hughes JA. Cationic Lipid Vectors for Plasmid DNA Delivery. Current Medicinal Chemistry. 2003; 10(14): 1185‐1193

[7] Felgner PL. Nonviral Strategies for Gene Therapy. Sci. Am. 1997; 276(6), 102‐106

[8] Remy JS, Sirlin C, Vierling P, Behr JP. Gene Transfer with a Series of Lipophilic DNA‐binding molecules. Bioconjugate Chem. 1994; 5, 647‐654

[9] Platscher M. DOTAP Enantiomers, Racemic and Enantiomerically Pure DOTAP Chloride. Merck Eprova AG. 2008; presentation

[10] Terp MC, Bauer F, Sugimoto Y, Yu B, Brueggemeier RW, Lee LJ, Lee, RJ. Differential Efficacy of DOTAP Enantiomers for siRNA Delivery in vitro. Int J Pharm. 2012; 430: 328‐334

[11] Hays LM, Crowe JH, Wolkers W, Rudenko S. Factors Affecting Leakage of Trapped Solutes from Phaospholipid Vesicles during Thermotropic Phase Transitions. Cryobiol. 2001; 42: 88‐102

[12] Vasievich EA, Chen W, Huang L. Enantiospecific Adjuvant Activity of Cationic Lipid DOTAP in Cancer Vaccine. Cancer Immunol Immunother. 2011; 60: 629‐638

[13] Vasievich EA, Ramishetti S, Zhang Y, Huang L. Trp2 Peptide Vaccine Adjuvant with (R)‐DOTAP Inhibits Tumor Growth in an Advanced Melanoma Model. Mol Pharmaceutics. 2012; 9(2): 261‐268

[14] PDS Biotechnology Corp. Press Release, October 6, 2009. (http://pdsbiotech.com/press_releases.html)

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