Millipore Sigma Vibrant Logo

852110 Fmoc-(Dmb)Gly-OH

Fmoc-(Dmb)Gly-OH Novabiochem®. CAS 166881-42-1, molar mass 447.48 g/mol.

Fmoc-(Dmb)Gly-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 166881-42-1 Molar Mass: 447.48 g/mol Hill Formula: C₂₆H₂₅NO₆
View Products on Sigmaaldrich.com
852110
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
166881-42-1C₂₆H₂₅NO₆447.48 g/mol

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
8521100001
Retrieving availability...
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Glass bottle 1 g
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      Description
      Catalogue Number852110
      Replaces04-12-1268
      Brand Family Novabiochem®
      Alternate Names
      • N-α-Fmoc-N-α-(2, 4-dimethoxybenzyl)-glycine
      Background InformationFmoc-(Dmb)Gly-OH is an excellent reagent for enhancing synthetic efficiency of glycine-containing peptides.

      Like the analogous Hmb derivative Fmoc-(FmocHmb)Gly-OH, the use of this derivative prevents aggregation during chain assemby, thereby leading to faster and more predictable acylation and deprotection reactions. Furthermore, it can prevent aspartimide formation when used to introduce a Gly immediately before an Asp residue and help promote cyclization of Gly-containing peptides [1].

      The analogous (Tmob)Gly derivative has been used by Bayer and colleagues to prepare a 64-residue transmembrane peptide in remarkable purity [2].

      The product number for this product was previously 04-12-1268.

      To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
      References
      Product Information
      CAS number166881-42-1
      Hill FormulaC₂₆H₂₅NO₆
      Molar Mass447.48 g/mol
      Structure formula ImageStructure formula Image
      Quality LevelMQ200
      Applications
      ApplicationFmoc-(Dmb)Gly-OH Novabiochem®. CAS 166881-42-1, molar mass 447.48 g/mol.
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Storage class10 - 13 Other liquids and solids
      WGKWGK 3 highly hazardous to water
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at -15°C to -25°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Color (visual)white to slight yellow to beige
      Appearance of substance (visual)powder
      Identity (IR)passes test
      Purity (TLC(157B))≥ 98 %
      Assay (HPLC, area%)≥ 99.0 % (a/a)
      Solubility (1 mmole in 2 ml DMF)passes test
      Assay (acidimetric)≥ 94.0 %
      Water (K. F.)≤ 1.00 %
      For TLC-Systems see our General Catalog
      Global Trade Item Number
      Catalogue Number GTIN
      8521100001 04027269089757

      Documentation

      Fmoc-(Dmb)Gly-OH SDS

      Title

      Safety Data Sheet (SDS) 

      Citations

      Title
      • [1] M. El Haddadi, et al. (2000) J. Pept. Sci., 6, 560 (2000) J. Pept. Sci., 6, 560.
      • [2] K. Jauch, et al. in "Peptides 1996: Proc. 24th European Peptide Symposium", R. Ramage and R. Epton (Eds), Mayflower Scientific Ltd., 1996, pp 497.