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39391

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide

Name: <I>N</I>-(3-Dimethylaminopropyl)-<I>N</I>&#8242;-ethylcarbodiimide
Brand: ALDRICH

≥97.0% (T), for peptide synthesis

Sinónimos:

N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide, EDC, WSC

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Acerca de este artículo

Fórmula empírica (notación de Hill):

C₈H₁₇N₃

Número CAS:

1892-57-5

Peso molecular:

155.24

NACRES:

NA.22

PubChem Substance ID:

57649895

UNSPSC Code:

12352116

EC Number:

217-579-2

MDL number:

MFCD00044916

Beilstein/REAXYS Number:

507429

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Propiedades

Nombre del producto

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide, ≥97.0% (T)

Quality Segment

100

assay

≥97.0% (T)

form

liquid

reaction suitability

reaction type: Coupling Reactions

refractive index

n20/D 1.460-1.463

density

0.877 g/mL at 20 °C (lit.)

application(s)

peptide synthesis

functional group

amine

storage temp.

−20°C

SMILES string

CCN=C=NCCCN(C)C

InChI

1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3

InChI key

LMDZBCPBFSXMTL-UHFFFAOYSA-N

Descripción

General description

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide is commonly used in combination with N-hydroxysuccinimide (NHS) in carbodiimide coupling reaction to activate carboxyl group for coupling with amines to form amides.

Application

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide has been used for the surface functionalization of graphene quantum dots (GQDs) employed as sensing probes in Janus micromotors to detect enterobacterial contamination. It has also been used for the activation of folic acid, prior to its conjugation on silica nanoparticles.