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Merck

05-903

Anti-GSK3α/β Antibody, rabbit monoclonal

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Nombre del producto

Anti-GSK3α/β Antibody, rabbit monoclonal, Upstate®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... GSK3A(2931)

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
routinely evaluated by immunoblot on lysates from HEK293 cells

Application

Anti-GSK3α/β Antibody is an antibody against GSK3α/β for use in IP & WB.

Biochem/physiol Actions

GSK3 alpha and beta
Predicted to cross-react with rat based on sequence homology

General description

Mr 46kDa (beta) and 51kDa (alpha)

Immunogen

N-terminal 6His-tagged recombinant full length human GSK3β

Physical form

Format: Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Yasuhiro Nishino et al.
Circulation research, 103(3), 307-314 (2008-06-28)
The inactivation of glycogen synthase kinase-3beta (GSK-3beta) is proposed as the event integrating protective pathways initiated by preconditioning and other interventions. The inactivation of GSK-3 is thought to decrease the probability of opening of the mitochondrial permeability transition pore. The
Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication.
Chuluunbaatar, U; Roller, R; Feldman, ME; Brown, S; Shokat, KM; Mohr, I
Genes & Development null
Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes.
Jope, Richard S
Trends in Pharmacological Sciences, 24, 441-443 (2003)
GSK-3 inhibitors: discoveries and developments.
Alonso, M and Martinez, A
Current Medicinal Chemistry, 11, 755-763 (2004)
The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth.
Dormoy, V; Danilin, S; Lindner, V; Thomas, L; Rothhut, S; Coquard, C; Helwig, JJ; Jacqmin et al.
Molecular Cancer null

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