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Merck

AB5559

Sigma-Aldrich

Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop

Chemicon®, from rabbit

Sinónimos:

Anti-CAE2, Anti-DEE74, Anti-ECA2, Anti-EIEE74, Anti-FEB8, Anti-GEFSP3

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GABRG2(2566)

Immunogen

Epitope: cytoplasmic loop
MBP fusion protein from the cytosolic loop of rat GABAA receptor gamma2 subunit.

Application

Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop detects level of GABA A Receptor γ2 & has been published & validated for use in IP & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1:1,000

Immunopreciptation: The antibody will immunoprecipitate 49% of all GABAA receptors in dodecylsulfate extracts of rat forebrains (150 μL) using 15 μg of antibody.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

GABAA receptor gamma2 subunit. Reacts with the ~44-47kDa gamma2 subunit of the GABAA receptor in rat brain membrane fractions.

Physical form

Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. Approximate concentration is 0.2 mg/mL.

Preparation Note

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Clase de almacenamiento

10 - Combustible liquids

wgk_germany

WGK 2


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The Lennox-Gastaut syndrome is a devastating early-onset epileptic encephalopathy, associated with severe behavioural abnormalities. Its pathophysiology, however, is largely unknown. A de novo mutation (c.G358A, p.D120N) in the human GABA type-A receptor β3 subunit gene (GABRB3) has been identified in

Número de artículo de comercio global

SKUGTIN
AB555904053252734304

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