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Merck

MAB858-1

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 133-1H

ascites fluid, clone 133-1H, from mouse

Sinónimos:

RSV

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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Nombre del producto

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 133-1H, ascites fluid, clone 133-1H, from mouse

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

133-1H, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable

isotype

IgG2a

shipped in

wet ice

Quality Level

Analysis Note

Control
RSV Control Slides, Catalogue Number 5012-5

Application

ELISA at 1:800+

Indirect Immunofluorescence at 1:100-200+ (fresh frozen tissue sections)

Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-RSV Antibody, fusion protein, all type A, B strains, clone 133-1H is validated for use in ELISA, IF for the detection of Respiratory Syncytial Virus.

Biochem/physiol Actions

Directed against the 47-49 kDa Fusion Protein of RSV. Antibody MAB858-1 recognizes both A and B RSV strains.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.

Immunogen

A2
Epitope: all type A & B strains

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Ascites fluid with 0.1% sodium azide as a preservative.
Unpurified

Preparation Note

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

nwg

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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E K Park et al.
Molecules and cells, 12(1), 50-56 (2001-09-20)
Respiratory syncytial virus (RSV) is one of the principal agents of bronchiolitis and pneumonia in young children. Thus, there is a strong need to make a safe and effective vaccine against the RSV infection. DNA immunization is very effective at
Bahar Ahani et al.
Nature communications, 14(1), 4347-4347 (2023-07-20)
Nirsevimab is a monoclonal antibody that binds to the respiratory syncytial virus (RSV) fusion protein. During the Phase 2b (NCT02878330) and MELODY (NCT03979313) clinical trials, infants received one dose of nirsevimab or placebo before their first RSV season. In this
Wy Ching Ng et al.
Journal of virology, 90(1), 206-221 (2015-10-16)
It is well established that influenza A virus (IAV) attachment to and infection of epithelial cells is dependent on sialic acid (SIA) at the cell surface, although the specific receptors that mediate IAV entry have not been defined and multiple
Natural infection of infants with respiratory syncytial virus subgroups A and B: a study of frequency, disease severity, and viral load.
Devincenzo, JP
Pediatric Research null
Elevated temperature triggers human respiratory syncytial virus F protein six-helix bundle formation.
Yunus, AS; Jackson, TP; Crisafi, K; Burimski, I; Kilgore, NR; Zoumplis, D; Allaway et al.
Virology null

Número de artículo de comercio global

SKUGTIN
MAB858-104053252724398

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