247588
Salicylic acid
ACS reagent grade, ≥99.0%
Sinónimos:
2-Hydroxybenzoic acid
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Fórmula lineal:
2-(HO)C6H4CO2H
Número CAS:
Peso molecular:
138.12
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-712-3
MDL number:
Beilstein/REAXYS Number:
774890
Assay:
≥99.0%
Servicio técnico
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Permítanos ayudarleNombre del producto
Salicylic acid, ACS reagent, ≥99.0%
grade
ACS reagent
Quality Level
vapor density
4.8 (vs air)
vapor pressure
1 mmHg ( 114 °C)
assay
≥99.0%
impurities
H2SO4, passes test (darkened)
ign. residue
≤0.01%
bp
211 °C (lit.)
mp
158-161 °C (lit.)
anion traces
chloride (Cl-): ≤0.001%, sulfate (SO42-): ≤0.003%
cation traces
Fe: ≤2 ppm, heavy metals (as Pb): ≤5 ppm
functional group
carboxylic acid
SMILES string
OC(=O)c1ccccc1O
InChI
1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChI key
YGSDEFSMJLZEOE-UHFFFAOYSA-N
Gene Information
human ... ALB(213), PTPN1(5770)
General description
Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.
Application
Salicylic acid has been used:
- as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
- as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)
Biochem/physiol Actions
Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 1
flash_point_f
314.6 °F - closed cup
flash_point_c
157 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Xanthone
AF Holleman
Organic Syntheses, 1, 552-552 (1941)
Isochorismate synthase is required to synthesize salicylic acid for plant defence
Wildermuth MC, et al.
Nature, 414(6863), 562-562 (2001)
A central role of salicylic acid in plant disease resistance
Delaney TP, et al.
Science, 266(5188), 1247-1250 (1994)