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Merck

73594

Ammonium acetate

LiChropur, eluent additive for LC-MS

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Fórmula lineal:
CH3CO2NH4
Número CAS:
Peso molecular:
77.08
NACRES:
NB.21
PubChem Substance ID:
eCl@ss:
39021908
UNSPSC Code:
41115710
EC Number:
211-162-9
MDL number:
Beilstein/REAXYS Number:
4186741
Assay:
≥99.0% (calc. on dry substance, T)
Form:
solid
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Quality Level

agency

suitable for ASTM® 7968, suitable for ASTM® 7979, suitable for DIN 38407-42, suitable for EPA 1633, suitable for EPA 533, suitable for EPA 537.1, suitable for EPA 8327, suitable for EPA ACB B21-02, suitable for EPA ACB B23-05b, suitable for GB 31604.35-2016, suitable for GB 5009.253-2016, suitable for ISO 21675 2019, suitable for ISO 25101, suitable for ISO/CEN 15968-2010

reg. compliance

suitable for FDA C-010.02

product line

LiChropur

assay

≥99.0% (calc. on dry substance, T)

form

solid

quality

LiChropur

technique(s)

LC/MS: suitable

impurities

insoluble matter, passes filter test, ≤1% water

ign. residue

≤0.01% (as SO4)

pH

6.2-7.5 (25 °C, 1 M in H2O)

mp

110-112 °C (dec.) (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤5 mg/kg, nitrate (NO3-): ≤10 mg/kg, sulfate (SO42-): ≤10 mg/kg

SMILES string

N.CC(O)=O

cation traces

Al: ≤1 mg/kg, As: ≤0.1 mg/kg, Ba: ≤1 mg/kg, Bi: ≤1 mg/kg, Ca: ≤5 mg/kg, Cd: ≤1 mg/kg, Co: ≤1 mg/kg, Cr: ≤1 mg/kg, Cu: ≤1 mg/kg, Fe: ≤1 mg/kg, K: ≤5 mg/kg, Li: ≤1 mg/kg, Mg: ≤1 mg/kg, Mn: ≤1 mg/kg, Mo: ≤1 mg/kg, Na: ≤5 mg/kg, Ni: ≤1 mg/kg, Pb: ≤1 mg/kg, Sr: ≤1 mg/kg, Zn: ≤1 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: ≤0.015, λ: 280 nm Amax: ≤0.010

suitability

passes test for LC-MS

application(s)

PFAS testing

InChI

1S/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3

InChI key

USFZMSVCRYTOJT-UHFFFAOYSA-N

General description

Ammonium acetate exists as a white crystal. It is prepared from acetic acid and ammonia by neutralization to pH 7.0. It is widely used in analytical chemistry, drugs and in textile dyeing.

Application

Ammonium acetate has been used to prepare eluents for UPLC-MS/MS and HPLC-MS/MS to compare the matrix effect of 9 pharmaceutical compounds in aqueous environmental samples. It has also been used as an additive to improve detection of phosphopeptides using MALDI-MS.

Legal Information

ASTM is a registered trademark of American Society for Testing and Materials
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Comparison of matrix effects in HPLC-MS/MS and UPLC-MS/MS analysis of nine basic pharmaceuticals in surface waters.
Van De Steene JC, Lambert WE.
Journal of the American Society For Mass Spectrometry, 19(5), 713-718 (2008)
Enhanced detection of phosphopeptides in matrix-assisted laser desorption/ionization mass spectrometry using ammonium salts.
Asara JM, Allison J.
Journal of the American Society For Mass Spectrometry, 10(1), 35-44 (1999)
Dale L. Perry
Handbook of Inorganic Compounds, 17-17 (1995)