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01148

Sodium fluoride

puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

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Fórmula lineal:
NaF
Número CAS:
7681-49-4
Peso molecular:
41.99
UNSPSC Code:
12352302
eCl@ss:
38050104
PubChem Substance ID:
329747226
EC Number:
231-667-8
NACRES:
NA.21
MDL number:
MFCD00003524
Assay:
98.5-100.5% (calc. to the dried substance)
Form:
powder
Servicio técnico
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vapor pressure

1.4 mmHg ( 0 °C)

Quality Level

200

grade

puriss.

assay

98.5-100.5% (calc. to the dried substance)

form

powder

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

acidity or alkalinity, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.002% heavy metals (as Pb), ≤0.1% free alkali (as NaOH), ≤0.2% free acid (as HF), ≤0.2% sodium hexafluorosilicate (Na2SiF6)

loss

≤0.5% loss on drying, 150 °C

mp

993 °C (lit.)

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤200 mg/kg

cation traces

Fe: ≤50 mg/kg

suitability

complies for appearance of solution

SMILES string

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

General description

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed preservative for glucose in blood. It has been reported to stabilize hepatic microsomal glucose-6-P phosphohydrolase enzyme.

Application

Sodium fluoride may be employed as fluorination agent in the synthesis of aromatic and aliphatic fluorides, via metathesis. It may be used to prepare the lysis buffer.

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pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

supp_hazards

EUH032

flash_point_f

Not applicable

flash_point_c

Not applicable

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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Certificados de análisis (COA)

Lot/Batch Number
STBK4579
STBL0919
STBK6711
STBK4450
STBK3254

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A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
J G Drachman et al.
The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)
c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells
Synthesis of fluorides by metathesis with sodium fluoride.
Tullock CW and Coffman DD.
The Journal of Organic Chemistry, 25(11), 2016-2019 (1960)
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